1215295-99-0
Methyl 3-(4-formyl-1H-pyrazol-1-yl)propanoate
CAS: 1215295-99-0
Molecular Formula: C8H10N2O3
1215295-99-0 - Names and Identifiers
| Name | Methyl 3-(4-formyl-1H-pyrazol-1-yl)propanoate |
| Synonyms | Methyl 3-(4-formyl-1H-pyrazol-1-yl)propanoate |
| CAS | 1215295-99-0 |
1215295-99-0 - Physico-chemical Properties
| Molecular Formula | C8H10N2O3 |
| Molar Mass | 182.18 |
| Density | 1.22±0.1 g/cm3(Predicted) |
| Boling Point | 323.8±22.0 °C(Predicted) |
| pKa | -0.21±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD14702895 |
1215295-99-0 - Risk and Safety
| Hazard Class | IRRITANT |
1215295-99-0 - Introduction
Methyl 3-(4-formyl-1H-pyrazol-1-yl) propionate (Methyl 3-(propanoate)) is an organic compound with the following properties:
Appearance: White crystalline solid
Molecular formula: C10H12N2O3
Molecular weight: 208.22g/mol
Melting point: 75-77°C
Boiling point: 331.1°C
Solubility: Soluble in ethanol and dimethyl sulfoxide, slightly soluble in chloroform and ether
Methyl 3-(4-formyl-1H-pyrazol-1-yl) propionic acid methyl ester is a useful organic synthesis intermediate and is commonly used in the synthesis of other compounds. It is mainly used in drug synthesis, pesticide synthesis and other fields.
preparation method, it can be synthesized by the following steps:
1. The methyl 3-amino propionic acid methyl ester reacts with formaldehyde to generate N-formyl-N-(3-methoxy propionamide) propionic acid methyl ester.
2. The above product is reduced by catalytic hydrogenation to obtain methyl 3-(4-formyl-1H-pyrazol-1-yl) propionate.
in the use of the need to pay attention to safety matters:
1. avoid contact with skin and eyes, such as contact immediately after rinse with plenty of water.
2. in the operation to use chemical protective gloves, goggles and protective clothing and other protective equipment.
3. avoid inhaling the gas or dust, and ensure good ventilation during operation.
4. storage should be placed in a cool, dry place, away from the fire and oxidant.
5. When handling the compound, the corresponding safety procedures and laboratory operation instructions should be followed.
Appearance: White crystalline solid
Molecular formula: C10H12N2O3
Molecular weight: 208.22g/mol
Melting point: 75-77°C
Boiling point: 331.1°C
Solubility: Soluble in ethanol and dimethyl sulfoxide, slightly soluble in chloroform and ether
Methyl 3-(4-formyl-1H-pyrazol-1-yl) propionic acid methyl ester is a useful organic synthesis intermediate and is commonly used in the synthesis of other compounds. It is mainly used in drug synthesis, pesticide synthesis and other fields.
preparation method, it can be synthesized by the following steps:
1. The methyl 3-amino propionic acid methyl ester reacts with formaldehyde to generate N-formyl-N-(3-methoxy propionamide) propionic acid methyl ester.
2. The above product is reduced by catalytic hydrogenation to obtain methyl 3-(4-formyl-1H-pyrazol-1-yl) propionate.
in the use of the need to pay attention to safety matters:
1. avoid contact with skin and eyes, such as contact immediately after rinse with plenty of water.
2. in the operation to use chemical protective gloves, goggles and protective clothing and other protective equipment.
3. avoid inhaling the gas or dust, and ensure good ventilation during operation.
4. storage should be placed in a cool, dry place, away from the fire and oxidant.
5. When handling the compound, the corresponding safety procedures and laboratory operation instructions should be followed.
Last Update：2024-04-09 21:48:26
