1216601-32-9 - Names and Identifiers
1216601-32-9 - Physico-chemical Properties
Molecular Formula | C16H18FN3O3
|
Molar Mass | 319.34 |
Melting Point | 217-220°C |
Solubility | DMSO (Slightly), Methanol (Very Slightly, Heated) |
Appearance | Solid |
Color | Off-White to Pale Yellow |
Storage Condition | -20°C Freezer |
Stability | Hygroscopic |
1216601-32-9 - Introduction
Norfloxacin-d8 (Norfloxacin-d8) is an isotopic marker of norfloxacin, its molecular formula is C16H15D8FN3O3, molecular weight of 341.4g/mol.
In terms of properties, Norfloxacin-d8 is a white crystalline solid that is soluble in some organic solvents, such as ethanol and dimethyl sulfoxide. Its melting point is about 221-225 degrees Celsius.
The Norfloxacin-d8 is mainly used for tracer experiments in pharmacokinetics and drug metabolism studies. It can be compared with the original norfloxacin molecule to study the metabolic process and in vivo excretion kinetics of drugs. Its application can also be used to develop and validate analytical methods. Because Norfloxacin-d8 is a marker, it is often used as an internal standard substance for the analysis of norfloxacin in living organisms.
preparation method, Norfloxacin-d8 is mainly prepared by deuterated substitution reaction. Specifically, the proton of norfloxacin will be replaced by deuteration, resulting in Norfloxacin-d8.
Safety information, Norfloxacin-d8 need to be stored in a dry, cool place, away from fire and oxidizing agents. During use, care should be taken to avoid inhalation, ingestion or contact with skin and eyes. In case of accidental contact or inhalation, rinse immediately with plenty of water and seek medical help.
Last Update:2024-04-10 22:30:50