1218790-78-3
(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid
CAS: 1218790-78-3
Molecular Formula: C14H22BN3O4
1218790-78-3 - Names and Identifiers
1218790-78-3 - Physico-chemical Properties
| Molecular Formula | C14H22BN3O4 |
| Molar Mass | 307.15 |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD13195677 |
1218790-78-3 - Introduction
(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid is an organic boron compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Usually white or off-white solid.
-Solubility: Soluble in many organic solvents, such as ethers, ketones and chlorinated hydrocarbons.
-Stability: relatively stable under dry conditions, but may be sensitive to air and moisture.
Use:
-Organic synthesis: boric acid reagents used in organic synthesis reactions. It can be used as a substrate or reagent to participate in different types of reactions, such as Suzuki coupling reaction, Heck reaction and C- H activation reaction.
Preparation Method:
(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl) The preparation of boronic acid usually involves the following steps:
1. Reaction of (2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid ester with sodium hydride in alcohol.
2. the resulting product is (2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid by acidification or alkalinization.
Safety Information:
-May be irritating to eyes, skin and respiratory tract, rinse with plenty of water immediately after contact. Seek medical help if necessary.
-Pay attention to appropriate personal protective measures during use, such as wearing gloves, safety glasses, etc.
-It must be operated in a well-ventilated place to avoid inhaling the dust or vapor of the compound.
-Store away from fire and oxidant, and avoid contact with air and moisture.
-Use and storage under the correct conditions to ensure the safe use of the compound.
Nature:
-Appearance: Usually white or off-white solid.
-Solubility: Soluble in many organic solvents, such as ethers, ketones and chlorinated hydrocarbons.
-Stability: relatively stable under dry conditions, but may be sensitive to air and moisture.
Use:
-Organic synthesis: boric acid reagents used in organic synthesis reactions. It can be used as a substrate or reagent to participate in different types of reactions, such as Suzuki coupling reaction, Heck reaction and C- H activation reaction.
Preparation Method:
(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl) The preparation of boronic acid usually involves the following steps:
1. Reaction of (2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid ester with sodium hydride in alcohol.
2. the resulting product is (2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid by acidification or alkalinization.
Safety Information:
-May be irritating to eyes, skin and respiratory tract, rinse with plenty of water immediately after contact. Seek medical help if necessary.
-Pay attention to appropriate personal protective measures during use, such as wearing gloves, safety glasses, etc.
-It must be operated in a well-ventilated place to avoid inhaling the dust or vapor of the compound.
-Store away from fire and oxidant, and avoid contact with air and moisture.
-Use and storage under the correct conditions to ensure the safe use of the compound.
Last Update：2024-04-09 15:18:10
