1219976-47-2 - Names and Identifiers
1219976-47-2 - Physico-chemical Properties
Molecular Formula | C13H13BrN2
|
Molar Mass | 277.16 |
Density | 1.419±0.06 g/cm3(Predicted) |
Boling Point | 372.7±42.0 °C(Predicted) |
pKa | 5.18±0.10(Predicted) |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD13562754 |
1219976-47-2 - Introduction
N-Benzyl-5-bromo-3-methyl-2-pyridinamine is an organic compound whose chemical formula is C12H12BrN3. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: A white to light yellow solid
-Melting point: about 98 ℃
-Solubility: Soluble in some organic solvents, such as methanol, ethanol and dichloromethane
-Stability: stable at room temperature, avoid prolonged exposure to strong light and high temperature conditions
Use:
N-Benzyl-5-bromo-3-methyl-2-pyridinamine is an organic synthesis intermediate used to prepare other compounds. Because its structure has a certain activity, it can be used in organic synthesis reactions, for example, as an amination reagent for substitution reactions to build new chemical bonds.
Preparation Method:
N-Benzyl-5-bromo-3-methyl-2-pyridinamine can be synthesized by the following methods:
1. reaction of p-toluenesulfonic acid and 5-bromo -2,3-dihydropyridine to generate 5-bromo -3-methyl -2-picolinic acid.
2. react the product obtained in the previous step with benzylamine to generate N-benzyl -5-bromo -3-methyl -2-pyridylamine.
3. Finally, benzoylation of N-benzyl -5-bromo-3-methyl-2-pyridinamine was carried out under alkaline conditions to obtain N-Benzyl-5-bromo-3-methyl-2-pyridinamine.
Safety Information:
Detailed information on N-Benzyl-5-bromo-3-methyl-2-pyridinamine toxicological information and related safety measures requires further research. However, as a chemical substance, it is recommended to take appropriate protective measures when using it, such as wearing gloves, glasses and laboratory coats, and avoid direct contact with skin and eyes. Also, work in a well-ventilated area to avoid inhalation or ingestion of the compound. Always follow the instructions in the chemical safety instructions for handling and storage.
Last Update:2024-04-10 22:29:15