1220020-60-9
4-Chloro-6-(3-pyrrolidinyloxy)pyrimidinehydrochloride
CAS: 1220020-60-9
Molecular Formula: C8H11Cl2N3O
1220020-60-9 - Names and Identifiers
| Name | 4-Chloro-6-(3-pyrrolidinyloxy)pyrimidinehydrochloride |
| Synonyms | 4-Chloro-6-(3-pyrrolidinyloxy)pyrimidinehydrochloride 4-CHLORO-6-(PYRROLIDIN-3-YLOXY)PYRIMIDINE HYDROCHLORIDE |
| CAS | 1220020-60-9 |
1220020-60-9 - Physico-chemical Properties
| Molecular Formula | C8H11Cl2N3O |
| Molar Mass | 236.1 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD13561254 |
1220020-60-9 - Introduction
4-Chloro-6-(3-pyrrolidinyloxy)pyrimidinehydrochloride (4-chloro-6-(3-pyrroloxy) pyrimidine hydrochloride) is an organic compound. Its molecular formula is C10H13ClN4O · HCl and its relative molecular mass is 292.16. The following is an introduction to its nature, use, preparation and safety information:
Nature:
4-Chloro-6-(3-pyrrolidinyloxy)pyrimidinehydrochloride are white crystals and hygroscopic. It can be dissolved in water and has good solubility.
Use:
4-Chloro-6-(3-Pyrrolidinyloxy) pyrimidinehydrochloride is mainly used as an intermediate in organic synthesis. It can be used in the preparation of various organic compounds, such as pharmaceutical synthesis, plant protection agents and dyes.
Preparation Method:
One method for preparing 4-Chloro-6-(3-pyrrolidinyloxy)pyrimidinehydrochloride is to react 3-bromopropyne with N-pyrrolidinyl-N-methylformamide to give 3-(3-pyrroloxy) propyne. The 3-(3-pyrroloxy) propyne is then reacted with an isocyanate to give 4-chloro-6-(3-pyrroloxy) pyrimidine. Finally, 4-chloro-6-(3-pyrroloxy) pyrimidine is reacted with hydrochloric acid to produce 4-Chloro-6-(3-pyrrolidinyloxy)pyrimidinehydrochloride.
Safety Information:
When handling 4-Chloro-6-(3-pyrrolidinyloxy)pyrimidinehydrochloride, take necessary safety precautions, such as wearing appropriate protective gloves, goggles, and protective clothing. Avoid inhaling its dust or solution and avoid skin contact. If contact occurs, rinse immediately with water and seek medical attention. In addition, it should be handled in a well-ventilated place and stored in a dry, dark, sealed container.
Nature:
4-Chloro-6-(3-pyrrolidinyloxy)pyrimidinehydrochloride are white crystals and hygroscopic. It can be dissolved in water and has good solubility.
Use:
4-Chloro-6-(3-Pyrrolidinyloxy) pyrimidinehydrochloride is mainly used as an intermediate in organic synthesis. It can be used in the preparation of various organic compounds, such as pharmaceutical synthesis, plant protection agents and dyes.
Preparation Method:
One method for preparing 4-Chloro-6-(3-pyrrolidinyloxy)pyrimidinehydrochloride is to react 3-bromopropyne with N-pyrrolidinyl-N-methylformamide to give 3-(3-pyrroloxy) propyne. The 3-(3-pyrroloxy) propyne is then reacted with an isocyanate to give 4-chloro-6-(3-pyrroloxy) pyrimidine. Finally, 4-chloro-6-(3-pyrroloxy) pyrimidine is reacted with hydrochloric acid to produce 4-Chloro-6-(3-pyrrolidinyloxy)pyrimidinehydrochloride.
Safety Information:
When handling 4-Chloro-6-(3-pyrrolidinyloxy)pyrimidinehydrochloride, take necessary safety precautions, such as wearing appropriate protective gloves, goggles, and protective clothing. Avoid inhaling its dust or solution and avoid skin contact. If contact occurs, rinse immediately with water and seek medical attention. In addition, it should be handled in a well-ventilated place and stored in a dry, dark, sealed container.
Last Update：2024-04-09 21:00:56
