122520-85-8 - Names and Identifiers
122520-85-8 - Physico-chemical Properties
Molecular Formula | C10H8N2O3
|
Molar Mass | 204.18 |
Density | 1.482±0.06 g/cm3(Predicted) |
Melting Point | 247 °C |
Boling Point | 544.4±50.0 °C(Predicted) |
Appearance | Brown solid. |
pKa | 8.81±0.10(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
In vitro study | (E)-AG 99 effectively blocks tyrosine phosphorylation of p145 met and promotes cell death accompanied by activation of caspase-like proteases. |
122520-85-8 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 4.898 ml | 24.488 ml | 48.976 ml |
5 mM | 0.98 ml | 4.898 ml | 9.795 ml |
10 mM | 0.49 ml | 2.449 ml | 4.898 ml |
5 mM | 0.098 ml | 0.49 ml | 0.98 ml |
Last Update:2024-01-02 23:10:35
122520-85-8 - Reference Information
use | tyrosine phosphorylation inhibitor A46 is mainly used as a pharmaceutical inhibitor. |
biological activity | AG99 (Tyrphostin 46,Tyrphostin A46,Tyrphostin B40) is an effective and selective EGFR inhibitor. |
target | TargetValue EGFR () |
Target | Value |
in vitro study | (E)-AG 99 effectively blocks tyrosine phosphorylation of p145 met and promotes cell death accompanied by activation of caspase-like proteases. |
Last Update:2024-04-09 21:21:28