1227587-24-7 - Names and Identifiers
1227587-24-7 - Physico-chemical Properties
Molecular Formula | C7H3ClF3NO2
|
Molar Mass | 225.55 |
Storage Condition | 2-8°C |
1227587-24-7 - Introduction
2-Chloro-3-trifluoromethylisonicotinic acid is an organic compound with the chemical formula C4ClF3NO2. The following is a description of its nature, use, preparation and safety information:
Nature:
2-Chloro-3-trifluoromethylisonicotinic acid is a colorless to pale yellow crystalline solid, soluble in organic solvents such as ethanol and ethereal solvents. It has high stability and heat resistance, and is relatively stable at room temperature.
Use:
2-Chloro-3-trifluoromethylisonicotinic acid is an important organic synthesis intermediate, which is widely used in organic synthesis reactions. It has good electrophilicity and can be used for substitution reaction, acylation reaction and cyclization reaction. It is often used to synthesize drugs, pesticides, dyes and other organic compounds.
Preparation Method:
2-chloro-3-trifluoromethyl isonicotinic acid can be prepared by the alkaline hydrolysis reaction of isocyanate. First, an appropriate amount of trifluoromethyl isocyanate and an appropriate amount of alkaline conditions, hydrolysis to generate 2-chloro-3-trifluoromethyl isonicotinic acid.
Safety Information:
2-Chloro-3-trifluoromethylisonicotinic acid is generally relatively safe under normal conditions of use. However, it can be irritating and injurious to the eyes and skin. Therefore, you should pay attention to protective measures, such as wearing appropriate protective glasses, gloves and laboratory coats, to avoid direct contact. At the same time, you should avoid inhaling its powder or gas, and maintain good ventilation conditions. In the process of handling and storage, avoid contact with harmful substances such as oxidants, strong acids or strong bases to prevent unsafe reactions.
Last Update:2024-04-09 21:11:58