1228670-06-1
(E)-Methyl 3-(4-chloropyridin-3-yl)acrylate
CAS: 1228670-06-1
Molecular Formula: C9H8ClNO2
1228670-06-1 - Names and Identifiers
| Name | (E)-Methyl 3-(4-chloropyridin-3-yl)acrylate |
| Synonyms | (E)-Methyl 3-(4-chloropyridin-3-yl)acrylate 2-Propenoic acid, 3-(4-chloro-3-pyridinyl)-, methyl ester |
| CAS | 1228670-06-1 |
1228670-06-1 - Physico-chemical Properties
| Molecular Formula | C9H8ClNO2 |
| Molar Mass | 197.62 |
| Density | 1.270±0.06 g/cm3(Predicted) |
| Boling Point | 298.3±25.0 °C(Predicted) |
| pKa | 2.48±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD15530297 |
1228670-06-1 - Risk and Safety
| Hazard Class | IRRITANT |
1228670-06-1 - Introduction
(E)-Methyl 3-(4-choropyridin-3-yl) acrylate is an organic compound with the chemical formula C10H8ClNO2.
Nature:
(E)-Methyl 3-(4-chroopyridin-3-yl) acrylate is a colorless to pale yellow liquid with a special smell. It has a density of about 1.27g/cm³, a boiling point of about 332°C (atmospheric pressure), and is insoluble in water at room temperature but soluble in organic solvents such as ethanol and chloroform.
Use:
(E)-Methyl 3-(4-chroopyridin-3-yl) acrylate is an important organic synthesis intermediate. It can be used to synthesize a variety of drugs, insecticides and pesticides. In addition, it can also be used as a raw material for organic dyes and photosensitive materials.
Preparation Method:
(E)-Methyl 3-(4-chloropyridin-3-yl)acrylate can be prepared by reacting 4-chloronicotinic acid with methyl methacrylate in the presence of a catalyst. The reaction is usually carried out under the protection of nitrogen gas under the appropriate conditions of temperature and time.
Safety Information:
The (E)-Methyl 3-(4-chroopyridin-3-yl) acrylate has low toxicity under normal conditions. However, as an organic synthesis intermediate, proper handling and storage measures should be taken to avoid direct contact with skin, eyes and mouth. Use and handle with good ventilation and wear appropriate protective equipment such as lab gloves and safety glasses. If accidental exposure or inhalation occurs, seek immediate assistance from a medical professional.
Nature:
(E)-Methyl 3-(4-chroopyridin-3-yl) acrylate is a colorless to pale yellow liquid with a special smell. It has a density of about 1.27g/cm³, a boiling point of about 332°C (atmospheric pressure), and is insoluble in water at room temperature but soluble in organic solvents such as ethanol and chloroform.
Use:
(E)-Methyl 3-(4-chroopyridin-3-yl) acrylate is an important organic synthesis intermediate. It can be used to synthesize a variety of drugs, insecticides and pesticides. In addition, it can also be used as a raw material for organic dyes and photosensitive materials.
Preparation Method:
(E)-Methyl 3-(4-chloropyridin-3-yl)acrylate can be prepared by reacting 4-chloronicotinic acid with methyl methacrylate in the presence of a catalyst. The reaction is usually carried out under the protection of nitrogen gas under the appropriate conditions of temperature and time.
Safety Information:
The (E)-Methyl 3-(4-chroopyridin-3-yl) acrylate has low toxicity under normal conditions. However, as an organic synthesis intermediate, proper handling and storage measures should be taken to avoid direct contact with skin, eyes and mouth. Use and handle with good ventilation and wear appropriate protective equipment such as lab gloves and safety glasses. If accidental exposure or inhalation occurs, seek immediate assistance from a medical professional.
Last Update：2024-04-09 20:52:54
