1231930-82-7

Name	2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimida
Synonyms	LY2835219 Bemaciclib(salt) LY2835219 mesylate LY2835219 Ms salt, Abemaciclib Ms salt 2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimida N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine,methanesulfonic acid N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine Methanesulfonate
CAS	1231930-82-7

Molecular Formula	C27H32F2N8.CH4O3S
Molar Mass	602.7
Solubility	Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to at least 25 mg/ml).
Appearance	solid
Color	Off-white
Storage Condition	-20℃
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Physical and Chemical Properties	Bioactive Abemaciclib (LY2835219) is a potent, selective CDK4 and CDK6 inhibitor with an IC50 of 2 nM and 10 nM, respectively, in a cell-free assay. Phase 3.