123910-26-9

123910-26-9 - Names and Identifiers

Name	N-BOC-D-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid
Synonyms	Boc-D-Tpi-OH RARECHEM BK PT 0086 Boc-D-1,2,3,4-Tetrahydronorharman-3-Carboxylic Acid N-ALPHA-T-BUTOXYCARBONYL-D-TRYPTOLINE-3-CARBOXYLIC ACID (R)-2-BOC-1,2,3,4-TETRAHYDRONORHARMANE-3-CARBOXYLIC ACID N-BOC-D-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid N-BOC-D-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE-3-CARBOXYLIC ACID N-ALPHA-T-BUTOXYCARBONYL-D-1,2,3,4-TETRAHYDRONORHAM-3-CARBOXYLIC ACID (R)-1,3,4,9-TETRAHYDRO-B-CARBOLINE-2,3-DICARBOXYLIC ACID 2-TERT-BUTYL ESTER N-ALPHA-(T-BUTYLOXYCARBONYL)-1,2,3,4-TETRAHYDRONORHARMAN-D-3-CARBOXYLIC ACID N-ALPHA-TERT-BUTYLOXYCARBONYL-1,2,3,4-TETRAHYDRONORHARMAN-D-3-CARBOXYLIC ACID
CAS	123910-26-9
InChI	InChI=1/C17H20N2O4/c1-17(2,3)23-16(22)19-9-13-11(8-14(19)15(20)21)10-6-4-5-7-12(10)18-13/h4-7,14,18H,8-9H2,1-3H3,(H,20,21)/p-1/t14-/m1/s1

123910-26-9 - Physico-chemical Properties

Molecular Formula	C17H20N2O4
Molar Mass	316.35
Density	1.322±0.06 g/cm3(Predicted)
Boling Point	525.6±50.0 °C(Predicted)
Flash Point	271.7°C
Vapor Presure	7.12E-12mmHg at 25°C
pKa	3.98±0.20(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,2-8°C

123910-26-9 - Risk and Safety

Hazard Symbols	Xi - Irritant
Safety Description	S24/25 - Avoid contact with skin and eyes.
HS Code	29339900
Hazard Class	IRRITANT

123910-26-9 - Introduction

N-tert-Butoxycarbonyl-D-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid, also known as N-BOC-D-1,2,3, 4-acidoxyl, is an organic compound.

Nature:
N-tert-Butoxycarbonyl-D-1,2,3, 4-tetrahydro-beta-carboline-3-carboxylic acid is a white solid with a substituted tetrahydro-β-carboline ring and a formic acid group in its chemical structure. Its molecular formula is C13H19NO4 and its molecular weight is 257.3g/mol. It is a compound with good solubility and can be dissolved in some organic solvents such as methanol and ethanol.

Use:
N-tert-butoxycarbonyl-D-1,2,3, 4-tetrahydro-beta-carboline-3-carboxylic acid is a commonly used intermediate compound, which is widely used in organic synthesis. It can be used as a raw material or skeleton in the synthesis of drugs, and is commonly used in the synthesis of various bioactive molecules, such as alkaloids.

Preparation Method:
N-tert-Butoxycarbonyl-D-1,2,3, 4-tetrahydro-beta-carboline-3-carboxylic acid can be synthesized by the following steps:
1. D-tryptophan(D-tryptophan) is reacted with tert-butyldimethylsilyl ammonium oxide to obtain N-tert-butyldimethylsilyl tryptophan.
2. Tert-butyl dimethylsilyl tryptophan is then reacted with bromoacetate to generate N-tert-butoxycarbonyl-D-1,2,3, 4-tetrahydro-beta-carboline -3-carboxylic acid.

Safety Information:
N-tert-butoxycarbonyl-D-1,2,3, 4-tetrahydro-beta-carboline-3-carboxylic acid is generally considered to be low toxic in use, but it is still necessary to pay attention to appropriate safety measures. It should be kept away from ignition and oxidizing agents, avoid contact with skin and eyes, and avoid inhalation or ingestion. Wear appropriate protective equipment such as chemical gloves and goggles during use. If there is accidental contact or discomfort, should be timely medical treatment.

Last Update：2024-04-09 02:00:41