1245792-51-1
BCI
CAS: 1245792-51-1
Molecular Formula: C22H23NO
1245792-51-1 - Names and Identifiers
| Name | BCI |
| Synonyms | BCI (E)-BCI BCI - NSC 150117 1H-Inden-1-one, 3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-, (2E)- |
| CAS | 1245792-51-1 |
1245792-51-1 - Physico-chemical Properties
| Molecular Formula | C22H23NO |
| Molar Mass | 317.42 |
| Solubility | DMSO : 125 mg/mL (393.80 mM; Need ultrasonic) |
| Storage Condition | -20℃ |
| Use | BCI is an allosteric inhibitor of dual specific phosphatase (DUSP). The EC50 of BCI specific inhibition of DUSP6 and DUSP1 was 13.3 and 8.0 μM respectively. BCI did not inhibit DUSP5. |
1245792-51-1 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.15 ml | 15.752 ml | 31.504 ml |
| 5 mM | 0.63 ml | 3.15 ml | 6.301 ml |
| 10 mM | 0.315 ml | 1.575 ml | 3.15 ml |
| 5 mM | 0.063 ml | 0.315 ml | 0.63 ml |
Last Update：2024-01-02 23:10:35
1245792-51-1 - Reference Information
| Use | BCI is an allosteric bispecific phosphatase (DUSP) inhibitor, the EC50 was 13.3 μm and 8.0 μm, respectively, in the cells of DUSP6 and dusp1. |
| biological activity | BCI ((E)-BCI, compound 1) it is an inhibitor of allosteric dual specificity phosphate (DUSP) with EC50 values of 13.3 μM and 8.0 μm for DUSP6 and DUSP1, respectively, in cells. |
| Target | Value |
| DUSP1 (Cell-free assay) | 8.0 μM(EC50) |
| DUSP6 (Cell-free assay) | 13.3 μM(EC50) |
Last Update：2024-04-09 21:04:16
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Product Name: BCI Visit Supplier Webpage Request for quotationCAS: 1245792-51-1
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Mobile: 18021002903
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Wechat: 18301782025
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