1250512-48-1 - Names and Identifiers
1250512-48-1 - Physico-chemical Properties
1250512-48-1 - Introduction
4-(2-Chloro-phenyl)-tetrahydro-pyran-4-carbonitrile is an organic compound with the chemical formula C12H12ClN.
Nature:
-Appearance: 4-(2-Chloro-phenyl)-tetrahydro-pyran-4-carbonitrile as a white crystalline solid.
-Melting point: approximately 85-87°C.
-Solubility: 4-(2-Chloro-phenyl)-tetrahydro-pyran-4-carbonitrile is soluble in common organic solvents.
Use:
4-(2-Chloro-phenyl)-tetrahydro-pyran-4-carbonitrile is mainly used in organic synthesis as a starting material for the synthesis of other organic compounds. It is commonly used in the preparation of pesticides, drugs, etc.
Method:
The synthesis of 4-(2-Chloro-phenyl)-tetrahydro-pyran-4-carbonitrile is usually carried out by the following steps:
-First, start with benzaldehyde and convert it into 2-chlorophenylmethanol through aldehyde alkylation.
-Then, 2-chlorophenylmethanol is reacted with tetrahydrofuran to generate 4-(2-chlorophenyl) tetrahydro-2H-pyran.
-Finally, 4-(2-chlorophenyl) tetrahydro-2H-pyran is reacted with cyanide to generate 4-(2-Chloro-phenyl)-tetrahydro-pyran-4-carbonitrile.
Safety Information:
Specific safety and toxicity information for 4-(2-Chloro-phenyl)-tetrahydro-pyran-4-carbonitrile is not available. Wear appropriate personal protective equipment such as lab gloves and goggles during handling and use. At the same time, make sure to operate under well-ventilated conditions and avoid inhalation or skin contact.
Last Update：2024-04-09 21:11:58