1251008-89-5
2-Azaspiro[5.5]undecane-2,9-dicarboxylicacid 2-tert-butyl ester
CAS: 1251008-89-5
Molecular Formula: C16H27NO4
1251008-89-5 - Names and Identifiers
1251008-89-5 - Physico-chemical Properties
| Molecular Formula | C16H27NO4 |
| Molar Mass | 297.39 |
| Density | 1.14±0.1 g/cm3(Predicted) |
| Boling Point | 435.3±38.0 °C(Predicted) |
| pKa | 4.75±0.20(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD18839241 |
1251008-89-5 - Introduction
2-Azaspiro[5.5]undecane-2,9-dicarboxylicacid 2-tert-butyl ester (abbreviated AZU) is an organic compound. Its chemical formula is C17H29NO5 and its molecular weight is 331.42g/mol.
Nature:
AZU is a solid with a white or off-white crystalline form. It has a high molecular symmetry and a relatively high melting point. AZU is soluble in many organic solvents, such as dimethyl sulfoxide and ethyl acetate.
Use:
AZU is widely used as an intermediate in organic synthesis. It can be used in the synthesis of biologically active natural products, drugs and ligands. Other applications include their use as synthetic intermediates for dyes and pigments.
Preparation Method:
The preparation method of AZU involves a series of chemical reactions, including nucleophilic substitution, cyclization and esterification. One of the common preparation methods is to use fatty acid and epoxy tert-butyl ether as starting materials, through aminolysis and esterification reaction, followed by alkylation to obtain the target product.
Safety Information:
AZU is generally considered to be relatively safe under normal conditions of use. However, during operation, it is necessary to observe the necessary safety measures to prevent contact with skin and eyes, and to avoid inhalation or ingestion. In potentially unsafe situations, wear appropriate personal protective equipment and operate in a well-ventilated area. Relevant safety procedures and laboratory practices need to be followed.
Nature:
AZU is a solid with a white or off-white crystalline form. It has a high molecular symmetry and a relatively high melting point. AZU is soluble in many organic solvents, such as dimethyl sulfoxide and ethyl acetate.
Use:
AZU is widely used as an intermediate in organic synthesis. It can be used in the synthesis of biologically active natural products, drugs and ligands. Other applications include their use as synthetic intermediates for dyes and pigments.
Preparation Method:
The preparation method of AZU involves a series of chemical reactions, including nucleophilic substitution, cyclization and esterification. One of the common preparation methods is to use fatty acid and epoxy tert-butyl ether as starting materials, through aminolysis and esterification reaction, followed by alkylation to obtain the target product.
Safety Information:
AZU is generally considered to be relatively safe under normal conditions of use. However, during operation, it is necessary to observe the necessary safety measures to prevent contact with skin and eyes, and to avoid inhalation or ingestion. In potentially unsafe situations, wear appropriate personal protective equipment and operate in a well-ventilated area. Relevant safety procedures and laboratory practices need to be followed.
Last Update：2024-04-09 20:45:29
