Molecular Formula | C30H35ClN4O2 |
Molar Mass | 519.0775 |
Solubility | DMSO: 6 mg/mL (Need ultrasonic or warming) |
Storage Condition | -20℃ |
Physical and Chemical Properties | The main properties of aletinib hydrochloride is a highly effective inhibitor of ALK kinase with an IC50 value of 1.9nM and is also sensitive to ALK mutant L1196M. |
Use | Uses Eratinib hydrochloride is a highly selective and effective anaplastic lymphoma kinase (ALK) inhibitor, which can block drug-resistant gatekeeper mutants and lead to decreased cell growth. It is also an intermediate of alitinib (C183360). Alitinib is a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor, which can block drug-resistant gatekeeper mutants and cause cell growth Slow down. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 1.926 ml | 9.632 ml | 19.265 ml |
5 mM | 0.385 ml | 1.926 ml | 3.853 ml |
10 mM | 0.193 ml | 0.963 ml | 1.926 ml |
5 mM | 0.039 ml | 0.193 ml | 0.385 ml |