1256633-18-7

1256633-18-7 - Names and Identifiers

Name	Methyl 3-amino-4-pyridazinecarboxylate
Synonyms	1-Butanesulfonicacid,5-hydroxy- Methyl 3-aminopyridazine-4-carboxylate Methyl 3-AMinopyridazine-4-carboxylate Methyl 3-amino-4-pyridazinecarboxylate 4-Pyridazinecarboxylic acid, 3-amino-, methyl ester
CAS	1256633-18-7
InChI	InChI=1S/C6H7N3O2/c1-11-6(10)4-2-3-8-9-5(4)7/h2-3H,1H3,(H2,7,9)

1256633-18-7 - Physico-chemical Properties

Molecular Formula	C6H7N3O2
Molar Mass	153.14
Density	1.319±0.06 g/cm3(Predicted)
Boling Point	353.4±22.0 °C(Predicted)
pKa	2.77±0.10(Predicted)
Storage Condition	2-8°C(protect from light)

1256633-18-7 - Introduction

3-amino pyridazine-4-carboxylic acid methyl ester, chemical name is N-(3-amino pyridazine-4-yl) carboxylic acid methyl ester, molecular formula is C7H9N5O2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
3-Aminopyridazine-4-carboxylic acid methyl ester is a colorless to light yellow solid with special chemical structure characteristics. It is stable at room temperature and pressure and soluble in polar organic solvents such as methanol and ethanol.

Use:
3-aminopyridazine-4-carboxylic acid methyl ester has anti-cancer activity and is commonly used in the pharmaceutical field as an anti-tumor drug synthesis intermediate. It can be used to synthesize DNA methyltransferase inhibitors, nucleoside anticancer drugs and other bioactive substances.

Method:
The preparation method of 3-aminopyridazine-4-carboxylic acid methyl ester is relatively simple, and is generally prepared by introducing an ester group on the aminopyridazine molecule for esterification. Specific steps may include reacting the aminopyridazine with methyl formate under acidic conditions to produce the desired product.

Safety Information:
When using and manipulating methyl 3-aminopyridazine-4-carboxylate, the following safety precautions should be taken:
1. use should wear appropriate personal protective equipment, such as gloves and goggles, avoid direct contact with the skin and eyes.
2. in the operation should maintain a well ventilated laboratory environment, try to avoid inhalation of dust or vapor compounds.
3. chemicals should be properly stored in a closed container, away from heat and fire sources.
4. Follow the relevant operating procedures and safety guidelines when handling chemicals.
5. In case of skin contact, inhalation or ingestion, rinse immediately with water and seek medical attention.

In general, 3-aminopyridazine-4-carboxylic acid methyl ester is a compound with special chemical structure and anti-cancer activity, which is commonly used in the pharmaceutical field as a drug synthesis intermediate. Pay attention to safe operation when using, avoid direct contact and inhalation of the compound.

Last Update：2024-04-09 19:05:46