1258226-87-7
Ombitasvir
CAS: 1258226-87-7
Molecular Formula: C50H67N7O8
1258226-87-7 - Names and Identifiers
| Name | Ombitasvir |
| Synonyms | ABT-267 Ombitasvir ombitasvir Viekira Pak) Ombitasvir(ABT-267) 2,2'-[[(2S,5S)-1-[4-(1,1-Dimethylethyl)phenyl]-2,5-pyrrolidinediyl]di-4,1-phenylene]bis[N-(methoxycarbonyl)-L-valyl-L-prolinamide L-Prolinamide, 2,2'-[[(2S,5S)-1-[4-(1,1-dimethylethyl)phenyl]-2,5-pyrrolidinediyl]di-4,1-phenylene]bis[N-(methoxycarbonyl)-L-valyl- |
| CAS | 1258226-87-7 |
1258226-87-7 - Physico-chemical Properties
| Molecular Formula | C50H67N7O8 |
| Molar Mass | 894.11 |
| Density | 1.223±0.06 g/cm3(Predicted) |
| Melting Point | >177°C (dec.) |
| Boling Point | 1065.6±65.0 °C(Predicted) |
| Solubility | DMSO: ≥ 33 mg/mL |
| Appearance | Solid |
| Color | Off-White to Pale Beige |
| pKa | 10.92±0.46(Predicted) |
| Storage Condition | -20°C Freezer, Under inert atmosphere |
| In vitro study | Ombitasvir (ABT-267) is an HCV NS5A inhibitor with picomolar inhibitory potency and broad activity against various genotypes, with an EC50 range of 0.82-19.3 pM for HCV genotypes 1-5, the EC50 of genotype 6a was 366 pM. The EC50 of Ombitasvir for the subgenomic replicon of genotypes 1a-H77 and 1b-Con1 were 14.1 and 5 pM, respectively. |
1258226-87-7 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.118 ml | 5.592 ml | 11.184 ml |
| 5 mM | 0.224 ml | 1.118 ml | 2.237 ml |
| 10 mM | 0.112 ml | 0.559 ml | 1.118 ml |
| 5 mM | 0.022 ml | 0.112 ml | 0.224 ml |
Last Update：2024-01-02 23:10:35
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Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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