1258296-60-4 - Names and Identifiers
1258296-60-4 - Physico-chemical Properties
| Molecular Formula | C17H14Cl2N6O
|
| Molar Mass | 389.24 |
| Density | 1.517±0.06 g/cm3(Predicted) |
| Solubility | ( < 1 mg/ml refers to the product slightly soluble or insoluble) |
| pKa | 10.48±0.70(Predicted) |
| Storage Condition | -20℃ |
| Use | RO495 is a potent inhibitor of TYK2 with IC50 of 1.5nM on TYK2 as tested in cell-based pharmacological assays。 |
1258296-60-4 - Preparation solution concentration reference
| | 1mg | 5mg | 10mg |
|---|
| 1 mM | 2.569 ml | 12.846 ml | 25.691 ml |
| 5 mM | 0.514 ml | 2.569 ml | 5.138 ml |
| 10 mM | 0.257 ml | 1.285 ml | 2.569 ml |
| 5 mM | 0.051 ml | 0.257 ml | 0.514 ml |
Last Update：2024-01-02 23:10:35
1258296-60-4 - Reference Information
| biological activity | RO495 (CS-2667) is an effective inhibitor of Non-receptor tyrosine-protein kinase 2 (TYK2). |
| target | TargetValue TYK2 () |
| Target | Value |
Last Update：2024-04-09 02:00:00
