1261869-76-4

1261869-76-4 - Names and Identifiers

Name	1-oxoisoindoline-5-carbonitrile
Synonyms	1-oxoisoindoline-5-carbonitrile 1-oxo-2,3-dihydroisoindole-5-carbonitrile 1-Oxo-2,3-dihydro-1H-isoindole-5-carbonitrile 1H-Isoindole-5-carbonitrile, 2,3-dihydro-1-oxo-
CAS	1261869-76-4
InChI	InChI=1S/C9H6N2O/c10-4-6-1-2-8-7(3-6)5-11-9(8)12/h1-3H,5H2,(H,11,12)

1261869-76-4 - Physico-chemical Properties

Molecular Formula	C9H6N2O
Molar Mass	158.16
Storage Condition	Sealed in dry,Room Temperature

1261869-76-4 - Introduction

5-Cyanoisoindolin-1-one, chemical formula C11H6N4O, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
1. appearance: 5-cyanoisoindoline -1-ketone is white or light yellow crystal.
2. Solubility: It is soluble in many organic solvents, but has poor solubility in water.
3. Thermal stability: It is relatively stable at high temperatures.

Use:
5-Cyanoisoindolin-1-one has a variety of applications:
1. Drug synthesis: It can be used as an intermediate for the synthesis of anti-tumor drugs, anti-infective drugs and antiviral drugs.
2. coordination chemistry: it can be used as a coordination reagent for the synthesis of metal complexes.

Method:
The preparation method of 5-cyanoisoindoline -1-ketone is more complicated, and a common preparation method is as follows:
Using indoline -1-one as starting material, it reacts with potassium cyanide to generate N-cyanoindoline -1-one, and then 5-cyanoisoindoline -1-one is obtained by amine-catalyzed reaction.

Safety Information:
1. 5-Cyanoisoindolin-1-one is an organic compound, which may have certain toxicity. Appropriate precautions should be taken during handling and use to avoid contact with skin and eyes.
2. should be stored in a cool, dry, well-ventilated place, away from fire and oxidant.
3. Comply with laboratory safety regulations during use and properly dispose of waste.

Last Update：2024-04-09 02:00:41