Name | 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDODICARBOCYANINE PERCHLORATE |
Synonyms | DILC18(5) 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDODICARBOCYANINE PERCHLORATE DiIC18(5) [DiD] [1,1'-Dioctadecyl-3,3,3',3'-tetraMethylindodicarbocyanine perchlorate] 3H-INDOLIUM, 2-[5-(1,3-DIHYDRO-3,3-DIMETHYL-1-OCTADECYL-2H-INDOL-2-YLIDENE)-1,3-PENTADIENYL]-3,3-DIMETHYL-1-OCTADECYL-, PERCHLORATE |
CAS | 127274-91-3 |
Molecular Formula | C61H99ClN2O4 |
Molar Mass | 860.4599 |
Solubility | Soluble in ethanol, methanol, dimethyl sulfoxide |
Appearance | Morphological crystals |
Color | Dark brown |
Storage Condition | −20°C |
Physical and Chemical Properties | Bioactive DiD perchlorate is a far red fluorescent lipophilic cyanine dye. DiD perchlorate can quickly and stably bind to phospholipid cell membrane and can be used for cell tracking. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 8 |
Reference Show more | 1. [IF=6.953] Qihong Zhang et al."Preparation, physicochemical and pharmacological study of 10-hydroxycamptothecin solid dispersion with complexation agent – xylan-nonanoic acid amphiphilic conjugates."Int J Biol Macromol. 2022 Apr;204:224 |
maximum wavelength (& lambda;max)
644 nm
biological applications
Detecting cell lysis,microorganisms,nucleic acids,lipid diffusion in giant unilamellar vesicles,lipid diffusion in phospholipid bilayers,lipids and proteins diffusion in membranes; monitoring cell migration
Two weeks after injection of stained cells, a single, bright, DiD perchlorate (DiD)-positive cells located between 15 to 40 µm from the endosteum is found. Results reveal a progressive appearance of cell clusters of decreased dye intensity, consistent with the partitioning of DiD perchlorate label on cell division.