1281674-64-3

1281674-64-3 - Names and Identifiers

Name	(2-Methyl-Piperidin-4-Yl)-Carbamic Acid Tert-Butyl Ester
Synonyms	tert-butyl (2-Methylpiperidin-4-yl)carbaMate tert-butyl N-(2-methylpiperidin-4-yl)carbamate (2-Methyl-Piperidin-4-Yl)-Carbamicacidtert-Butylester (2-METHYL-PIPERIDIN-4-YL)-CARBAMICACIDTERT-BUTYLESTER (2-Methyl-Piperidin-4-Yl)-Carbamic Acid Tert-Butyl Ester Carbamic acid, N-(2-methyl-4-piperidinyl)-, 1,1-dimethylethyl ester
CAS	1281674-64-3

1281674-64-3 - Physico-chemical Properties

Molecular Formula	C11H22N2O2
Molar Mass	214.3
Density	1.00±0.1 g/cm3(Predicted)
Boling Point	313.4±31.0 °C(Predicted)
pKa	12.40±0.40(Predicted)
Storage Condition	2-8°C(protect from light)

1281674-64-3 - Introduction

(2-Methyl-piperidine-4-aminoacetic acid tert-butyl ester, also known as tert-butyl maprol ester, is an organic compound. It has the following properties:

1. appearance: colorless liquid.
2. Density: about 0.9 g/mL.
3. Melting point: about -76°C.
4. Boiling point: about 215°C.
5. Solubility: Soluble in many organic solvents, such as ethanol, ether and chloroform.

(2-methyl-piperidine -4-) amino acetic acid tert-butyl ester is mainly used as follows:

1. pharmaceutical field: as a local anesthetic and anesthetic aid, can be used for eye surgery and skin local anesthesia.
2. pesticide field: as an intermediate in the synthesis of pesticides.
3. chemical research field: used in organic synthesis research, is a commonly used organic reagent.

(2-methyl-piperidine -4-) amino acetic acid tert-butyl ester preparation method can generally be carried out by the following steps:

1. (2-methyl-piperidine -4-) amine and tert-butyl chloroacetate are reacted in an appropriate solvent, and the commonly used solvent is dimethylformamide.
2. After the reaction, the product is obtained by crystallization or condensation.
3. Finally, the obtained product was purified and dried by filtrate and washing.

Regarding the safety information of (2-methyl-piperidine-4-aminoacetic acid tert-butyl ester, the following matters should be noted:

1. avoid inhalation of vapor or spray, should be used in a well-ventilated place.
2. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water and seek medical attention.
3. avoid prolonged or repeated exposure to avoid chronic toxic effects.
4. fire extinguishing agent should be selected according to the surrounding environment, can use carbon dioxide, foam or dry powder fire.
5. storage should be sealed, away from the fire and oxidant.

When using and handling tert-butyl (2-methyl-piperidine-4-) aminoacetate, it is important to observe the relevant safety practices and refer to the safety data sheet for laboratory chemicals.

Last Update：2024-04-09 21:21:28