128199-93-9
Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-
CAS: 128199-93-9
Molecular Formula: C18H21N3O
128199-93-9 - Names and Identifiers
| Name | Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)- |
| Synonyms | 128199-93-9 5-HT3 antagonist 2 Spiro[1-azabicyclo[2.2.2]octane-3,5'(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)- |
| CAS | 128199-93-9 |
128199-93-9 - Physico-chemical Properties
| Molecular Formula | C18H21N3O |
| Molar Mass | 295.39 |
| Density | 1.36±0.1 g/cm3(Predicted) |
| Boling Point | 490.4±35.0 °C(Predicted) |
| pKa | 11.29±0.40(Predicted) |
| In vitro study | 5-HT3 antagonist 2 is from the reference compound 21k. |
128199-93-9 - Introduction
Spiro[1-azabicyclo[2.2.2]octane-3,5 '(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-is an organic compound with the following properties and uses:
properties: the chemical name of the compound is 1-chlorine -2,2-dimethyl -1-nitroethane, and the molecular formula is C5H10ClNO2. It is a colorless liquid with a volatile and pungent odor. It has a density of about 1.19g/cm3, a boiling point of 107-108°C, and a melting point of -55°C.
use: Spiro[1-azabicyclo[2.2.2]octane-3,5 '(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-widely used in organic synthesis reactions, as an important intermediate of reagents and catalysts. It can be used to produce pesticides, drugs, dyes and other organic compounds.
Preparation method: The preparation method of the compound is generally prepared by reacting 2,2-dimethylpropanal with hydrogen chloride acid under appropriate conditions. Specific reaction conditions and steps can be adjusted according to actual needs.
Safety information: Because Spiro[1-azabicyclo[2.2.2]octane-3,5 '(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-is irritating, wear appropriate personal protective equipment, such as goggles and gloves. Care should be taken to avoid inhalation, swallowing or contact with skin during operation. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. At the same time, it should be stored in a closed container, away from fire and high temperature. If necessary, consult the safety data sheets of the relevant material for more detailed safety information.
properties: the chemical name of the compound is 1-chlorine -2,2-dimethyl -1-nitroethane, and the molecular formula is C5H10ClNO2. It is a colorless liquid with a volatile and pungent odor. It has a density of about 1.19g/cm3, a boiling point of 107-108°C, and a melting point of -55°C.
use: Spiro[1-azabicyclo[2.2.2]octane-3,5 '(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-widely used in organic synthesis reactions, as an important intermediate of reagents and catalysts. It can be used to produce pesticides, drugs, dyes and other organic compounds.
Preparation method: The preparation method of the compound is generally prepared by reacting 2,2-dimethylpropanal with hydrogen chloride acid under appropriate conditions. Specific reaction conditions and steps can be adjusted according to actual needs.
Safety information: Because Spiro[1-azabicyclo[2.2.2]octane-3,5 '(4'H)-oxazole], 2'-(1-methyl-1H-indol-3-yl)-is irritating, wear appropriate personal protective equipment, such as goggles and gloves. Care should be taken to avoid inhalation, swallowing or contact with skin during operation. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. At the same time, it should be stored in a closed container, away from fire and high temperature. If necessary, consult the safety data sheets of the relevant material for more detailed safety information.
Last Update：2024-04-09 21:11:58
