128717-77-1

128717-77-1 - Names and Identifiers

Name	7-METHOXY-1H-INDOLE-3-CARBOXYLIC ACID
Synonyms	7-METHOXYINDOLE-3-CARBOXYLIC ACID 7-Methoxyindole-2-carboxylic acid 7-METHOXY-1H-INDOLE-3-CARBOXYLIC ACID 1H-Indole-3-carboxylicacid, 7-Methoxy-
CAS	128717-77-1
InChI	InChI=1/C10H9NO3/c1-14-8-4-2-3-6-7(10(12)13)5-11-9(6)8/h2-5,11H,1H3,(H,12,13)

128717-77-1 - Physico-chemical Properties

Molecular Formula	C10H9NO3
Molar Mass	191.18
Density	1.381g/cm³
Boling Point	447.6°C at 760 mmHg
Flash Point	224.5°C
Vapor Presure	8.54E-09mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.677

128717-77-1 - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed

128717-77-1 - Introduction

7-Methoxy-1H-indole-3-carboxylic acid is an organic compound with the chemical formula C12H11NO3. The following is a brief description of its nature, use, preparation and safety information:

Nature:
-Appearance: 7-Methoxy-1H-indole-3-carboxylic acid is a white to pale yellow crystalline solid.
-Melting point: about 132-134 ℃.
-Solubility: Soluble in common organic solvents, such as ethanol, chloroform and dichloromethane. Slightly soluble in water.

Use:
-7-Methoxy-1H-indole-3-carboxylic acid is an important intermediate in organic synthesis.
-It can be used to synthesize compounds with different biological activities, such as drugs, plant pesticides and dyes.
-The structure of the compound contains indole ring and carboxylic acid functional group, which makes it have potential application value in the field of pharmacy and pesticide.

Preparation Method:
The preparation of-7-methoxy-1H-indole-3-carboxylic acid is usually achieved by the methylation reaction of indole.
-A common preparation method is to react indole with methanol and sulfuric acid under appropriate conditions, and then partially reduce the carboxylic acid in the produced product to alcohol under the action of alkali.

Safety Information:
-7-Methoxy-1H-indole-3-carboxylic acid is a chemical that needs to be stored properly and handled in accordance with relevant regulations.
-Appropriate personal protective measures should be taken during use, preparation or storage, such as wearing protective glasses, chemical-resistant gloves and protective clothing.
-The compound is irritating to the eyes and skin, and direct contact should be avoided.
-If the substance is inhaled or ingested, seek medical attention immediately and provide details of the compound.
-Incident handling and waste disposal should follow proper chemical handling procedures and regulations.

Last Update：2024-04-09 02:00:41