129488-55-7
N-(4-Aminophenyl)-4-(tert-butyl)benzamide
CAS: 129488-55-7
Molecular Formula: C17H20N2O
129488-55-7 - Names and Identifiers
129488-55-7 - Physico-chemical Properties
| Molecular Formula | C17H20N2O |
| Molar Mass | 268.35 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD02063072 |
129488-55-7 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
129488-55-7 - Introduction
N-(4-Aminophenyl)-4-(tert-butyl)benzamide(N-(4-aminophenyl)-4-(tert-butyl)benzamide) is an organic compound whose chemical structure contains a benzene ring and a phenylcarbonylamine group. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White to light yellow crystal
-Molecular formula: C19H22N2O
-Molecular weight: 294.39g/mol
-Melting point: 145-150 degrees Celsius
-Solubility: This compound is soluble in some organic solvents, such as dimethylsulfinamide (DMSO) and dichloromethane (DCM).
Use:
- N-(4-Aminophenyl)-4-(tert-butyl)benzamide can be used to synthesize other organic compounds, such as drugs, dyes and polymer compounds.
-It can also be used as a catalyst, ligand or intermediate in organic synthesis.
Preparation Method:
- N-(4-Aminophenyl)-4-(tert-butyl)benzamide can be synthesized by the following steps:
1. Hydroquinone is reacted with tert-butyl alcohol to obtain p-tert-butyl phenol.
2. In the presence of thionyl chloride, p-tert-butylphenol and hydroquinone were condensed by thermal condensation reaction to obtain N-(4-tert-butylphenyl)-1,4-benzoquinone.
3. Finally, N-(4-Aminophenyl)-4-(tert-butyl)benzamide was obtained by aminolysis of N-(4-tert-butylphenyl)-1,4-benzoquinone.
Safety Information:
- N-(4-Aminophenyl)-4-(tert-butyl)benzamide should be operated under well-ventilated laboratory conditions.
-The compound may be irritating to the eyes and skin, and direct contact should be avoided when in contact.
-In handling and use, attention should be paid to personal protective measures, such as wearing laboratory gloves, laboratory glasses and laboratory coats.
-Waste disposal should be carried out in accordance with local regulations to avoid pollution to the environment.
Nature:
-Appearance: White to light yellow crystal
-Molecular formula: C19H22N2O
-Molecular weight: 294.39g/mol
-Melting point: 145-150 degrees Celsius
-Solubility: This compound is soluble in some organic solvents, such as dimethylsulfinamide (DMSO) and dichloromethane (DCM).
Use:
- N-(4-Aminophenyl)-4-(tert-butyl)benzamide can be used to synthesize other organic compounds, such as drugs, dyes and polymer compounds.
-It can also be used as a catalyst, ligand or intermediate in organic synthesis.
Preparation Method:
- N-(4-Aminophenyl)-4-(tert-butyl)benzamide can be synthesized by the following steps:
1. Hydroquinone is reacted with tert-butyl alcohol to obtain p-tert-butyl phenol.
2. In the presence of thionyl chloride, p-tert-butylphenol and hydroquinone were condensed by thermal condensation reaction to obtain N-(4-tert-butylphenyl)-1,4-benzoquinone.
3. Finally, N-(4-Aminophenyl)-4-(tert-butyl)benzamide was obtained by aminolysis of N-(4-tert-butylphenyl)-1,4-benzoquinone.
Safety Information:
- N-(4-Aminophenyl)-4-(tert-butyl)benzamide should be operated under well-ventilated laboratory conditions.
-The compound may be irritating to the eyes and skin, and direct contact should be avoided when in contact.
-In handling and use, attention should be paid to personal protective measures, such as wearing laboratory gloves, laboratory glasses and laboratory coats.
-Waste disposal should be carried out in accordance with local regulations to avoid pollution to the environment.
Last Update：2024-04-09 21:00:56
