129592-99-0
2-Amino-2-(4-Bromophenyl)Acetic Acid
CAS: 71079-03-3;129592-99-0
Molecular Formula: C8H8BrNO2
129592-99-0 - Names and Identifiers
129592-99-0 - Physico-chemical Properties
| Molecular Formula | C8H8BrNO2 |
| Molar Mass | 230.06 |
| Density | 1.673±0.06 g/cm3(Predicted) |
| Melting Point | 273-274° |
| Boling Point | 363.2±32.0 °C(Predicted) |
| Flash Point | 173.5°C |
| Vapor Presure | 6.51E-06mmHg at 25°C |
| pKa | 1.81±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Sensitive | Irritant |
| Refractive Index | 1.624 |
| MDL | MFCD00049327 |
129592-99-0 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| Hazard Class | IRRITANT |
129592-99-0 - Introduction
2-Amino-2-(4-Bromophenyl)Acetic Acid is an organic compound with the chemical formula C8H8BrNO2.
Nature:
-Appearance: White crystalline solid
-Melting point: about 150-152°C
-Solubility: Soluble in water, ethanol and acetone, insoluble in non-polar solvents such as ether and petroleum ether.
-Molecular weight: 216.06g/mol
Use:
-Chemical reagent: 2-Amino-2-(4-Bromophenyl)Acetic Acid is commonly used as a starting reagent or intermediate in organic synthesis.
-Drugs: It can be used in the field of medicine to synthesize drugs, such as anti-pain and anti-inflammatory drugs.
Preparation Method:
Generally, 2-Amino-2-(4-Bromophenyl)Acetic Acid can be prepared by the following steps:
1. p-Bromobenzene ether is reacted with sodium hydroxide to obtain p-bromophenol (4-Bromophene).
2. p-Bromophenol is reacted with bromoacetic acid to obtain 2-bromo-2-(4-bromophenyl) acetic acid.
3. Finally, 2-bromo-2-(4-bromophenyl) acetic acid is reacted with aqueous ammonia to obtain 2-Amino-2-(4-Bromophenyl)Acetic Acid.
Safety Information:
- 2-Amino-2-(4-Bromophenyl)Acetic Acid is an organic compound, and safety should be paid attention to during operation.
-During use, avoid inhaling its dust or contact with skin and eyes.
-Avoid contact with oxidants, acids or bases to prevent reaction.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during use or operation.
-Seek medical advice immediately if you have any discomfort or questions.
Nature:
-Appearance: White crystalline solid
-Melting point: about 150-152°C
-Solubility: Soluble in water, ethanol and acetone, insoluble in non-polar solvents such as ether and petroleum ether.
-Molecular weight: 216.06g/mol
Use:
-Chemical reagent: 2-Amino-2-(4-Bromophenyl)Acetic Acid is commonly used as a starting reagent or intermediate in organic synthesis.
-Drugs: It can be used in the field of medicine to synthesize drugs, such as anti-pain and anti-inflammatory drugs.
Preparation Method:
Generally, 2-Amino-2-(4-Bromophenyl)Acetic Acid can be prepared by the following steps:
1. p-Bromobenzene ether is reacted with sodium hydroxide to obtain p-bromophenol (4-Bromophene).
2. p-Bromophenol is reacted with bromoacetic acid to obtain 2-bromo-2-(4-bromophenyl) acetic acid.
3. Finally, 2-bromo-2-(4-bromophenyl) acetic acid is reacted with aqueous ammonia to obtain 2-Amino-2-(4-Bromophenyl)Acetic Acid.
Safety Information:
- 2-Amino-2-(4-Bromophenyl)Acetic Acid is an organic compound, and safety should be paid attention to during operation.
-During use, avoid inhaling its dust or contact with skin and eyes.
-Avoid contact with oxidants, acids or bases to prevent reaction.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during use or operation.
-Seek medical advice immediately if you have any discomfort or questions.
Last Update：2024-04-09 21:00:56
