1297537-41-7

1297537-41-7 - Names and Identifiers

Name	(S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile
Synonyms	4-[1-[(2S)-2-aminopropyl]pyrazol-3-yl]-2-chloro-benzonitrile (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitri... 4-[1-[(2S)-2-aminopropyl]-1H-pyrazol-3-yl]-2-chlorobenzonitrile Benzonitrile, 4-[1-[(2S)-2-aminopropyl]-1H-pyrazol-3-yl]-2-chloro- 4-[1-[(2S)-2-aminopropyl]pyrazol-3-yl]-2-chloro-benzonitrile(For export only)
CAS	1297537-41-7

1297537-41-7 - Physico-chemical Properties

Molecular Formula	C13H13ClN4
Molar Mass	260.72
Density	1.28±0.1 g/cm3(Predicted)
Boling Point	450.0±45.0 °C(Predicted)
pKa	8.82±0.10(Predicted)

1297537-41-7 - Upstream Downstream Industry

Downstream Products

ORM-15341

1297537-41-7 - Introduction

(S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile, also known as (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile, it is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline solid
-Molecular formula: C15H14ClN5
-Molecular weight: 297.76g/mol
-Melting point: 172-174 degrees Celsius
-Solubility: Soluble in chloroform, dichloromethane and ethanol, insoluble in water.

Use:
- (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile is a cholesteryl ester transfer protein (CETP) inhibitor.
-It can be used to study the biological processes related to cholesterol metabolism and cholesterol transport.

Method:
There are many ways to prepare (S)-4-(1-(2-aminoppyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile, one of which is common as follows:
-First, 2-chlorobenzonitrile and (S)-2-amino-1-propanol are reacted to form a transition compound.
-Then, the transition compound is reacted with (S)-4-3-(1H-pyrazol-3-yl) pyrrolcyclopentadiene to produce the target product.

Safety Information:
(S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile is a toxic substance, you need to pay attention to the following matters when using:
-Avoid contact with skin and eyes. Wear protective gloves, goggles and protective clothing when using.
-Use in a well-ventilated place to avoid inhaling aerosols or dust.
-Storage should be separated from flammable substances and oxidants to avoid sources of fire.
-In the event of inhalation, ingestion or skin contact, immediately take appropriate first aid measures and seek medical advice.

Last Update：2024-04-10 22:29:15