130309-37-4 - Names and Identifiers
130309-37-4 - Physico-chemical Properties
Molecular Formula | C24H25NO4
|
Molar Mass | 391.46 |
Density | 1.279±0.06 g/cm3(Predicted) |
Boling Point | 592.4±33.0 °C(Predicted) |
Appearance | White powder |
Color | White |
pKa | 3.98±0.20(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
MDL | MFCD00191201 |
130309-37-4 - Risk and Safety
130309-37-4 - Introduction
Fmoc-L-octahydroindoline-2-carboxylic acid is an organic compound with a chemical formula of C19H20N2O4 and a molecular weight of 336.37. The following is a description of the properties, uses, preparation and safety information of Fmoc-L-octahydroindoline-2-carboxylic acid:
Nature:
-Appearance: Fmoc-L octahydroindoline-2-carboxylic acid is a white to off-white crystalline powder.
-Melting point: about 160-163°C.
-Solubility: It has good solubility in common organic solvents, such as dimethyl sulfoxide and dimethylformamide.
Use:
- Fmoc-L-octahydroindoline-2-carboxylic acid is commonly used in peptide synthesis in solid-phase synthetic chemistry.
-As a precursor of Fmoc-L-octahydroindoline-2-carboxylic acid-N-anhydride, it is used to synthesize Fmoc-L-octahydroindoline-2-carboxylic acid-N-anhydride intermediate.
Preparation Method:
-The preparation of Fmoc-L-octahydroindoline-2-carboxylic acid usually uses L-octahydroindoline-2-carboxylic acid as a starting material. L-octahydroindoline-2-carboxylic acid is first converted to Fmoc-L-octahydroindoline-2-carboxylic acid by a nucleophilic substitution reaction.
Safety Information:
- Fmoc-L-Octahydroindoline-2-carboxylic acid has limited toxicological data, so it is necessary to pay attention to safety during operation. It may cause irritation to the skin, eyes and respiratory system, so wear appropriate personal protective equipment (such as gloves, goggles and masks) when exposed.
-When using or storing Fmoc-L octahydroindoline-2-carboxylic acid, operate in a well-ventilated place and away from fire and oxidizing agents. When handling this compound, follow the relevant safety practices.
Last Update:2024-04-10 22:29:15