130406-36-9

130406-36-9 - Names and Identifiers

Name	(R)-(2-Amino-1-phenyl-ethyl)-carbamic acid benzyl ester
Synonyms	(S)-N-Cbz-2-amino-1-phenylethylamine benzyl (S)-(2-amino-1-phenylethyl)carbamate (S)-(2-Amino-1-phenylethyl)-carbamic acid benzyl ester (R)-(2-Amino-1-phenyl-ethyl)-carbamic acid benzyl ester (S)-(2-Amino-1-phenyl-ethyl)-carbamic acid benzyl ester (S)-(2-AMINO-1-PHENYLETHYL)-CARBAMIC ACID PHENYLMETHYL ESTER Carbamic acid, N-[(1S)-2-amino-1-phenylethyl]-, phenylmethyl ester
CAS	130406-36-9

130406-36-9 - Physico-chemical Properties

Molecular Formula	C16H18N2O2
Molar Mass	270.33
Storage Condition	2-8°C(protect from light)

130406-36-9 - Introduction

(S)-(2-Amino-1-phenylethyl)-carbamic acid benzyl ester is an organic compound, also known as Pacoto solution (Peptide Bulk -2) or PB-2. Its chemical formula is C18H22N2O2.

Nature:
(S)-(2-Amino-1-phenylethyl)-formic acid benzyl ester is a colorless to light yellow solid, soluble in ethanol, chloroform and dichloromethane at ambient temperature. It is a chiral molecule with a central chiral carbon and exists as an enantiomer, the (S) enantiomer being the active form.

Use:
(S)-(2-amino-1-phenylethyl)-benzyl formate is commonly used as a raw material for the synthesis of peptide medicines, especially for the synthesis of antimicrobial peptides. It has antibacterial, bactericidal and regulating immune function.

Preparation Method:
(S)-(2-Amino-1-phenylethyl)-formate benzyl ester is generally prepared by chemical synthetic methods. A common method is to react benzyl alcohol with 2-aminoacetic acid to give (S)-(2-amino-1-phenylethyl)-acetic acid, which is then condensed with formic anhydride to give (S)-(2-amino-1-phenylethyl)-carboxylic acid benzyl ester.

Safety Information:
When using or handling benzyl (S)-(2-amino-1-phenylethyl)-formate, care should be taken to follow safe operating procedures. It may be irritating to the eyes, skin and respiratory tract, so care should be taken to avoid direct contact. At the same time, you should maintain a well-ventilated laboratory environment to avoid inhaling its dust or vapor. If there is accidental contact or inhalation, should immediately rinse with water, and timely medical treatment.

Last Update：2024-04-09 21:11:58