13104-56-8

13104-56-8 - Names and Identifiers

Name	4'-(4-methoxyphenyl)-2,2',6',2''-terpyridine
Synonyms	6',2''-terpyridin 6',2''-terpyridine 4'-(4-Methoxyphenyl)-2,2' 4'-(4-Méthoxyphényl)-2,2' 4'-(4-methoxyphenyl)-2,2',6',2''-terpyridine 2,6-Di[2-pyridyl-4-(p-methoxyphenyl)pyridine 4-(p-Methoxyphenyl)-2,6-di(2-pyridyl)pyridine 4-(4-methoxyphenyl)-2,6-dipyridin-2-ylpyridine 2,6-Di(2-pyridinyl)-4-(4-methoxyphenyl)pyridine
CAS	13104-56-8 337511-97-4
InChI	InChI=1/C22H17N3O/c1-26-18-10-8-16(9-11-18)17-14-21(19-6-2-4-12-23-19)25-22(15-17)20-7-3-5-13-24-20/h2-15H,1H3

13104-56-8 - Physico-chemical Properties

Molecular Formula	C22H17N3O
Molar Mass	339.39
Density	1.174±0.06 g/cm3(Predicted)
Melting Point	167-168℃
Boling Point	504.5±50.0 °C(Predicted)
Flash Point	178.9°C
Water Solubility	Insoluble in water.
Vapor Presure	8.27E-10mmHg at 25°C
Appearance	White powder
pKa	4.62±0.22(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.616
MDL	MFCD06796987

13104-56-8 - Introduction

4 '-(4-methoxyphenyl)-2,2':6 ',2 "-terpyridine is an organic compound with the chemical formula C19H17NO. Its properties, uses, preparation methods and safety information are as follows:

Nature:
-Appearance: White to yellowish crystalline powder.
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide, dichloromethane and ethanol, slightly soluble in water.
-Melting point: about 144-147 ℃.
-Structure: It is a terpyridine compound with a methoxyphenyl substituent group.

Use:
- 4 '-(4-methoxyphenyl)-2,2':6 ',2 ''-terpyridine is often used as a ligand in the field of organic synthesis to participate in metal-catalyzed reactions, such as nickel-catalyzed olefin activation.
-It can also be used to synthesize biologically active compounds and drug molecules.

Preparation Method:
The method of preparing 4 '-(4-methoxyphenyl)-2,2':6 ',2 ''-terpyridine can be obtained through a multi-step reaction. A commonly used method is:
1. 4-methoxybenzoic acid was synthesized from benzoic acid by acylation, reduction, methanesulfonic acid and iodination.
2. the required 3-(4-methoxyphenyl) acetone is synthesized by 4-methoxybenzoic acid and acetone through acetone ketopropion reaction.
3. Finally, 3-(4-methoxyphenyl) acetone was reacted with aniline by coupling reaction to obtain the target product 4 '-(4-methoxyphenyl)-2,2':6 ',2 "-terpyridine.

Safety Information:
- 4 '-(4-methoxyphenyl)-2,2':6 ',2 ''-terpyridine should be stored in a dry, low temperature place to avoid moisture and prolonged exposure to air.
-Wear appropriate protective equipment during operation, such as lab gloves, safety goggles, etc.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-When used in the laboratory, the corresponding safety procedures should be observed.

Last Update：2024-04-09 21:00:56