1313403-49-4
7-BIA
CAS: 1313403-49-4
Molecular Formula: C15H18O6
1313403-49-4 - Names and Identifiers
| Name | 7-BIA |
| Synonyms | 7-BIA |
| CAS | 1313403-49-4 |
1313403-49-4 - Physico-chemical Properties
| Molecular Formula | C15H18O6 |
| Molar Mass | 294.3 |
| Appearance | Solid |
| Storage Condition | 2-8°C，密封，干燥 |
| In vitro study | 7-BIA (7-butoxy illudalic acid analog) inhibits recombinant human PTPRD and recombinant human PTPRS with IC 50 values of ~1–3 μM and 40 μM, respectively. |
1313403-49-4 - Reference Information
| biological activity | 7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor, the IC50 value was approximately 1-3 μm. |
| Target | IC50: ~ 1-3 μm (PTPRD), 40 μm (PTPRS) |
| Animal Model: | WT mice (available cocaine 50 times, 1 mg/kg infusions on FR1 schedule during ≥20 prior sessions) |
| Dosage: | 10 mg/kg, 20 mg/kg |
| Administration: | Given i.p.; only once |
| Result: | Reduced cocaine self-administration in highly experienced WT mice. |
Last Update：2024-04-09 20:49:11
