1314394-96-1
2-Boc-octahydrocyclopenta[c]-pyrrole-3a-carboxylic acid
CAS: 1314394-96-1
Molecular Formula: C13H21NO4
1314394-96-1 - Names and Identifiers
1314394-96-1 - Physico-chemical Properties
| Molecular Formula | C13H21NO4 |
| Molar Mass | 255.31 |
| Storage Condition | 2-8℃ |
1314394-96-1 - Introduction
2-[(tert-butoxy) carbonyl]-octahydrocyclopenta [C] pyrrole-3a-carboxylic acid is an organic compound, its structure contains an eight-membered ring as well as T-butoxy and carbonyl groups. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless or white crystalline solid
-molecular formula: C12H21NO4
-Molecular weight: 243.3g/mol
-Melting Point: about 132-134 ℃
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and dichloromethane, insoluble in water
Use:
-Drug synthesis: 2-[(tert-butoxy) carbonyl]-octahydrocyclopenta [C] pyrrole-3a-carboxylic acid can be used as an intermediate for drug synthesis. For example, it can be used to synthesize precursors of eight-ring hybrid representative compounds, which have biological activities such as anti-tumor and anti-bacterial activities.
-Chemical reagent: It can also be used as a protecting group in organic synthesis to protect functional groups such as amino and hydroxyl groups.
Method:
2-[(tert-butoxy) carbonyl]-octahydrocyclopenta [C] pyrrole-3a-carboxylic acid is generally prepared by organic synthesis methods, the following is a common preparation method:
1. Reaction of phosphorus pentachloride and n-butanol to obtain butyl trichlorophosphine.
2. N-butyl pyrrolidine phosphate is obtained by reacting butyl trichlorophosphine with sodium pyrrole base.
3. N-butyl pyrrolidine phosphate is hydrolyzed to obtain N-butyl-pyrrolidine phosphate.
4. Reacting N-butyl-pyrrolidine phosphoric acid with diethylaminoacetic anhydride to generate 2-acetyl-octahydrocyclopenta [C] pyrrole-3a-carboxylic acid.
5. Finally, by reacting with tert-butanol, the target product [c]-pyrrole-3a-carboxylic acid is obtained.
Safety Information:
2-[(tert-butoxy) carbonyl]-octahydrocyclopenta [C] pyrrole-3a-carboxylic acid The following safety precautions should be taken when using and handling:
-Contact with skin, eyes and mucous membranes should be avoided. In case of contact, rinse immediately with plenty of water.
-Avoid dust and mist during operation or storage.
-Personal protective devices such as protective gloves, goggles and face shields should be used.
-It should be operated in a well-ventilated place to avoid inhaling its volatiles.
-It should be stored in a dry, ventilated place away from sources of fire.
Nature:
-Appearance: Colorless or white crystalline solid
-molecular formula: C12H21NO4
-Molecular weight: 243.3g/mol
-Melting Point: about 132-134 ℃
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and dichloromethane, insoluble in water
Use:
-Drug synthesis: 2-[(tert-butoxy) carbonyl]-octahydrocyclopenta [C] pyrrole-3a-carboxylic acid can be used as an intermediate for drug synthesis. For example, it can be used to synthesize precursors of eight-ring hybrid representative compounds, which have biological activities such as anti-tumor and anti-bacterial activities.
-Chemical reagent: It can also be used as a protecting group in organic synthesis to protect functional groups such as amino and hydroxyl groups.
Method:
2-[(tert-butoxy) carbonyl]-octahydrocyclopenta [C] pyrrole-3a-carboxylic acid is generally prepared by organic synthesis methods, the following is a common preparation method:
1. Reaction of phosphorus pentachloride and n-butanol to obtain butyl trichlorophosphine.
2. N-butyl pyrrolidine phosphate is obtained by reacting butyl trichlorophosphine with sodium pyrrole base.
3. N-butyl pyrrolidine phosphate is hydrolyzed to obtain N-butyl-pyrrolidine phosphate.
4. Reacting N-butyl-pyrrolidine phosphoric acid with diethylaminoacetic anhydride to generate 2-acetyl-octahydrocyclopenta [C] pyrrole-3a-carboxylic acid.
5. Finally, by reacting with tert-butanol, the target product [c]-pyrrole-3a-carboxylic acid is obtained.
Safety Information:
2-[(tert-butoxy) carbonyl]-octahydrocyclopenta [C] pyrrole-3a-carboxylic acid The following safety precautions should be taken when using and handling:
-Contact with skin, eyes and mucous membranes should be avoided. In case of contact, rinse immediately with plenty of water.
-Avoid dust and mist during operation or storage.
-Personal protective devices such as protective gloves, goggles and face shields should be used.
-It should be operated in a well-ventilated place to avoid inhaling its volatiles.
-It should be stored in a dry, ventilated place away from sources of fire.
Last Update：2024-04-09 21:00:56
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Product Name: 2-Boc-octahydrocyclopenta[c]-pyrrole-3a-carboxylic acid Visit Supplier Webpage Request for quotation
CAS: 1314394-96-1
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Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 1314394-96-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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