1314700-36-1 - Names and Identifiers
| Name | 2-([1,1'-biphenyl]-3-yl)propan-2-amine hydrochloride
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| Synonyms | 2-([1,1'-biphenyl]-3-yl)propan-2-amine hydrochloride
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| CAS | 1314700-36-1
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1314700-36-1 - Introduction
2-([1,1 '-biphenyl]-3-yl)propan-2-amine hydrochloride (also known as 2-([1,1'-biphenyl]-3-yl) propylamine hydrochloride) it is an organic compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C16H17N.HCl
-Molecular weight: 283.78g/mol
-Melting Point: 132-134 ℃
-Soluble: Soluble in water, ethanol and chloroform
Use:
- 2-([1,1 '-biphenyl]-3-yl)-2-methylpropionic acid can be used as an intermediate in the pharmaceutical field for the synthesis of drugs and bioactive molecules. It is often used in drug research to synthesize anti-cancer drugs, antiviral drugs and neurotransmitter modulators.
Method:
The synthesis method of -2-([1,1 '-biphenyl]-3-yl)-2-methylpropionic acid can be carried out by the following steps:
1. 1-bromobiphenyl reacts with malonic dianhydride to obtain biphenyl malonic dianhydride.
2. Biphenylmalonic dianhydride is reacted with benzylamine in the presence of basic conditions to give 2-([1,1 '-biphenyl]-3-yl)-2-methylpropanoic acid.
3. Finally, 2-([1,1 '-biphenyl]-3-yl)-2-methylpropionic acid is reacted with hydrochloric acid to generate 2-([1,1'-Biphenyl]-3-yl)-2-methylpropionic acid hydrochloride.
Safety Information:
- 2-([1,1 '-biphenyl]-3-yl)-2-methylpropionic acid is a chemical that should be followed by normal laboratory safety practices.
-Take appropriate precautions when handling the compound, such as wearing protective gloves and glasses.
-Avoid inhaling dust, contact with skin and eyes, etc.
-Keep it away from ignition sources and combustible materials during storage and handling.
-In case of swallowing or accidental contact, please seek medical attention and show the relevant materials to the doctor.
Last Update：2024-04-09 02:00:51