13156-04-2
1-tert-Butylazetidin-3-ol
CAS: 13156-04-2
Molecular Formula: C7H15NO
13156-04-2 - Names and Identifiers
| Name | 1-tert-Butylazetidin-3-ol |
| Synonyms | N-T-BUTYL-3-AZETIDINOL N-tert-Butyl-3-azetidinol 1-tert-Butylazetidin-3-ol 1-tert-Butyl-3-azetidinol N-T-BUTYL-3-HYDROXYAZETIDINE N-TERT-BUTYL-3-HYDROXYAZETIDINE 1-(1,1-Dimethylethyl)azetidin-3-ol 3-Azetidinol, 1-(1,1-dimethylethyl)- |
| CAS | 13156-04-2 |
| InChI | InChI=1/C7H15NO/c1-7(2,3)8-4-6(9)5-8/h6,9H,4-5H2,1-3H3 |
13156-04-2 - Physico-chemical Properties
| Molecular Formula | C7H15NO |
| Molar Mass | 129.2 |
| Density | 1.031±0.06 g/cm3(Predicted) |
| Melting Point | 45-46 °C |
| Boling Point | 169.2±33.0 °C(Predicted) |
| Flash Point | 31.9°C |
| Vapor Presure | 0.507mmHg at 25°C |
| pKa | 14.41±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.505 |
13156-04-2 - Risk and Safety
| Hazard Class | IRRITANT |
13156-04-2 - Introduction
N-tert-butyl-3-hydroxyazetidine is an organic compound with the chemical formula C5H11NO. The following is an introduction to its nature, use, preparation and safety information:
Nature:
N-tert-butyl-3-hydroxyazetidine is a colorless liquid. It has a melting point of -47°C and a boiling point of 85-87°C. It is volatile at room temperature and easily dissolves in water and most organic solvents.
Use:
N-tert-butyl-3-hydroxyazetidine is mainly used as an intermediate in organic synthesis. It can be used in the preparation of various drugs, pesticides and dyes and other organic compounds. In addition, it can also be used to prepare surfactants, polymers and other functional materials.
Preparation Method:
The preparation of N-tert-butyl-3-hydroxyazetidine can be achieved by a skeleton transfer reaction or a nucleophilic substitution reaction. The common method is to use nitrated tert-butylamine to react with 1,2-difluoroethane, and obtain the target product after alkali catalysis.
Safety Information:
N-tert-butyl-3-hydroxyazetidine is a relatively safe compound under general use conditions. Its LD50 (median lethal dose) value is 3200 mg/kg in experimental animals, indicating its low toxicity. However, care should be taken to avoid inhalation, ingestion or skin contact. During operation, wear protective gloves, goggles and protective mask to ensure good ventilation. In case of accidental leakage, corresponding emergency measures shall be taken, and relevant laws and regulations shall be followed for treatment and cleaning.
Nature:
N-tert-butyl-3-hydroxyazetidine is a colorless liquid. It has a melting point of -47°C and a boiling point of 85-87°C. It is volatile at room temperature and easily dissolves in water and most organic solvents.
Use:
N-tert-butyl-3-hydroxyazetidine is mainly used as an intermediate in organic synthesis. It can be used in the preparation of various drugs, pesticides and dyes and other organic compounds. In addition, it can also be used to prepare surfactants, polymers and other functional materials.
Preparation Method:
The preparation of N-tert-butyl-3-hydroxyazetidine can be achieved by a skeleton transfer reaction or a nucleophilic substitution reaction. The common method is to use nitrated tert-butylamine to react with 1,2-difluoroethane, and obtain the target product after alkali catalysis.
Safety Information:
N-tert-butyl-3-hydroxyazetidine is a relatively safe compound under general use conditions. Its LD50 (median lethal dose) value is 3200 mg/kg in experimental animals, indicating its low toxicity. However, care should be taken to avoid inhalation, ingestion or skin contact. During operation, wear protective gloves, goggles and protective mask to ensure good ventilation. In case of accidental leakage, corresponding emergency measures shall be taken, and relevant laws and regulations shall be followed for treatment and cleaning.
Last Update：2024-04-09 20:52:54
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CAS: 13156-04-2
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Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 13156-04-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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