133057-83-7

133057-83-7 - Names and Identifiers

Name	4-Benzyloxy-3-fluorobenzeneboronic acid
Synonyms	AKOS BRN-0078 1-formylphenylboronic acid 4-Benzyloxy-3-fluorophenylboro 4-BENZYLOXY-3-FLUOROPHENYLBORONIC ACID 4-Benzyloxy-3-fluorophenylboronic acid 4-BENZYLOXY-3-FLUOROBENZENEBORONIC ACID 4-Benzyloxy-3-fluorobenzeneboronic acid (3-FLUORO-4-BENZYLOXYPHENYL)BORONIC ACID
CAS	133057-83-7
EINECS	675-638-1
InChI	InChI=1/C13H12BFO3/c15-12-8-11(14(16)17)6-7-13(12)18-9-10-4-2-1-3-5-10/h1-8,16-17H,9H2

133057-83-7 - Physico-chemical Properties

Molecular Formula	C13H12BFO3
Molar Mass	246.04
Density	1.26±0.1 g/cm3(Predicted)
Melting Point	116 °C
Boling Point	428.0±55.0 °C(Predicted)
Flash Point	212.6°C
Solubility	soluble in Methanol
Vapor Presure	4.37E-08mmHg at 25°C
Appearance	White to bright yellow powder
Color	White to Almost white
pKa	7.61±0.17(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.577
MDL	MFCD00994627

133057-83-7 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing.
HS Code	29310095
Hazard Class	IRRITANT

133057-83-7 - Introduction

4-benzyloxy-3-fluorophenylboronic acid is an organoboron compound whose chemical formula is C7H7FO2B. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 4-benzyloxy-3-fluorophenylboronic acid is a white solid.
-Solubility: It has good solubility in common organic solvents, such as ethanol, dimethylformamide and dichloromethane.
-Melting point: Its melting point is about 130-132°C.
-Stability: It is relatively stable under normal conditions.

Use:
-4-benzyloxy-3-fluorophenylboronic acid is mainly used for boron esterification in organic synthesis. It can react with different organic compounds to form the corresponding boron esters. Boron esters are an important class of organic intermediates that can be used to construct carbon-carbon and carbon-oxygen bonds to synthesize a variety of organic compounds.

Preparation Method:
-4-benzyloxy-3-fluorophenylboronic acid can be prepared by the reaction of benzyl alcohol and 3-fluorophenylboronic acid. The specific synthesis method can refer to the relevant organic synthesis literature.

Safety Information:
-4-benzyloxy-3-fluorophenylboronic acid has limited specific toxicity data, but as a chemical substance, it should comply with general laboratory safety and protective measures. During operation, direct contact with skin and eyes should be avoided to avoid irritation or damage. Therefore, it is not recommended to use or handle this chemical in a home or non-professional environment. In order to ensure safety, please follow the correct use and disposal of chemicals, and please refer to the relevant safety data sheet.

Last Update：2024-04-10 22:29:15