13338-49-3

13338-49-3 - Names and Identifiers

Name	2-(Chloromethyl)-4,5-dihydro-1H-imidazole hydrochloride
Synonyms	Nsc187479 [50342-08-0], C4H7ClN2,118.03 5-Methanesulfonyl-2,3-dihydro-1H-indole 5-(methylsulfonyl)-2,3-dihydro-1H-indole 2-(Chloromethyl)-4,5-dihydro-1H-imidazole HCl 2-(chloromethyl)-4,5-dihydro-mono-,hydrochloride 2-CHLOROMETHYL-4,5-DIHYDROIMIDAZOLE HYDROCHLORIDE 2-(CHLOROMETHYL)-4,5-DIHYDRO-1H-IMIDAZOLE HYDROCHLORIDE 2-(Chloromethyl)-4,5-dihydro-1H-imidazole hydrochloride 1H-IMIDAZOLE, 2-(CHLOROMETHYL)-4,5-DIHYDRO-MONOHYDROCHLORIDE
CAS	13338-49-3
EINECS	641-883-8
InChI	InChI=1/C4H7ClN2.ClH/c5-3-4-6-1-2-7-4;/h1-3H2,(H,6,7);1H

13338-49-3 - Physico-chemical Properties

Molecular Formula	C4H8Cl2N2
Molar Mass	155.03
Melting Point	195-197
Boling Point	258.4℃ at 760mmHg
Appearance	Solid
Storage Condition	Room Temprature
MDL	MFCD04115823

13338-49-3 - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant

13338-49-3 - Introduction

2-Chloromethylimidazoline hydrochloride, chemical formula C5H6ClN3.HCl, is an organic compound.

Nature:
1. Appearance: colorless crystal or powder.
2. melting point: about 150-160 degrees Celsius.
3. Solubility: Soluble in water, ethanol and other organic solvents.

Use:
1. drug intermediates: 2-chloromethylimidazoline hydrochloride can be used to synthesize a variety of drugs, such as antiviral drugs, anticancer drugs.
2. chromatographic analysis: can be used as ion pair reagent for liquid chromatography.

Preparation Method:
2-Chloromethylimidazoline hydrochloride is usually synthesized by the following steps:
1.2-amino methyl imidazoline and hydrochloric acid are reacted to generate 2-amino methyl imidazoline hydrochloride.
2. The hydrochloride obtained reacts with thionyl chloride to generate 2-chloromethylimidazoline hydrochloride.
3. Pure 2-chloromethylimidazoline hydrochloride is obtained by crystallization or other purification methods.

Safety Information:
1. 2-Chloromethylimidazoline hydrochloride may be irritating to the eyes, skin, respiratory system and digestive system, and should be rinsed with plenty of water immediately after contact.
2. during use or operation, should wear appropriate protective equipment, such as chemical safety glasses, gloves and protective mask.
3. should avoid contact with strong oxidants.
4. storage should be sealed, dry, dark preservation, away from fire and heat sources.
5. in the use of the process should pay attention to the operation specification and the correct disposal.

Last Update：2024-04-09 02:00:42