1334298-90-6
Itacitinib
CAS: 1334298-90-6
Molecular Formula: C26H23F4N9O
1334298-90-6 - Names and Identifiers
1334298-90-6 - Physico-chemical Properties
| Molecular Formula | C26H23F4N9O |
| Molar Mass | 553.51 |
| Density | 1.57±0.1 g/cm3(Predicted) |
| Solubility | DMSO: ≥ 30 mg/mL |
| pKa | 11.66±0.50(Predicted) |
| Storage Condition | -20℃ |
| In vitro study | INCB039110 is a potent, selective JAK1 inhibitor, with 20 and 200-fold greater selectivity for JAK1 than for JAK2 and JAK3, respectively. The activities against JAK1, 2, 3 and TYK2 were 2, 63, >2000 and 795 nM, respectively. |
| In vivo study | The use of clinical doses of INCB039110, either alone or in combination with a toxic agent such as gemcitabine, prevents tumor growth in mice bearing pancreatic xenograft tumors. |
1334298-90-6 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.807 ml | 9.033 ml | 18.066 ml |
| 5 mM | 0.361 ml | 1.807 ml | 3.613 ml |
| 10 mM | 0.181 ml | 0.903 ml | 1.807 ml |
| 5 mM | 0.036 ml | 0.181 ml | 0.361 ml |
Last Update：2024-01-02 23:10:35
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Product Name: Itacitinib Visit Supplier Webpage Request for quotationCAS: 1334298-90-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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