1335210-34-8
(4R,12aS)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxylic acid
CAS: 1335210-34-8
Molecular Formula: C14H16N2O6
1335210-34-8 - Names and Identifiers
1335210-34-8 - Physico-chemical Properties
| Molecular Formula | C14H16N2O6 |
| Molar Mass | 308.29 |
| Density | 1.50±0.1 g/cm3(Predicted) |
| Boling Point | 560.8±50.0 °C(Predicted) |
| pKa | 5.52±0.40(Predicted) |
1335210-34-8 - Introduction
(4R,12aS)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxylic acid is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless crystalline solid
-Molecular formula: C14H15N3O5
-Molecular weight: 305.29g/mol
-Melting point: about 190-192°C
-Solubility: Slightly soluble in water, soluble in ethanol and dimethyl sulfoxide
Use:
- (4R,12aS)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxylic acid is a pharmaceutical intermediate commonly used in the preparation of antibiotic drugs.
Preparation Method:
The preparation methods of the compound are diverse and involve multi-step reactions. Here is one of the common synthetic routes:
1. 3,4-diiodo -5-aminopyridine was converted into 3,4-dimethoxy -5-aminopyridine with proper amount of methylene chloride and sodium hydroxide.
2. The amide compound is prepared by reacting 3,4-dimethoxy-5-aminopyridine with alkanal.
3. Complete intermediate steps with some organic reagents, such as epoxidation, substitution, etc.
4. The resulting intermediate is reacted with an appropriate amount of substrate to produce the final product.
Safety Information:
Safety information regarding (4R,12aS)-7-Methoxy-4-methyll-6, 8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxylic acid is currently limited, so it should be used with caution. Appropriate personal protective measures, such as wearing protective goggles, gloves and laboratory coats, are required for laboratory operations. In addition, proper handling and storage of all chemicals should be followed to ensure that they do not pose a hazard to humans or the environment. When using this compound, it is recommended to refer to the relevant literature and safety data forms for more detailed information on its safe use.
Nature:
-Appearance: Colorless crystalline solid
-Molecular formula: C14H15N3O5
-Molecular weight: 305.29g/mol
-Melting point: about 190-192°C
-Solubility: Slightly soluble in water, soluble in ethanol and dimethyl sulfoxide
Use:
- (4R,12aS)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxylic acid is a pharmaceutical intermediate commonly used in the preparation of antibiotic drugs.
Preparation Method:
The preparation methods of the compound are diverse and involve multi-step reactions. Here is one of the common synthetic routes:
1. 3,4-diiodo -5-aminopyridine was converted into 3,4-dimethoxy -5-aminopyridine with proper amount of methylene chloride and sodium hydroxide.
2. The amide compound is prepared by reacting 3,4-dimethoxy-5-aminopyridine with alkanal.
3. Complete intermediate steps with some organic reagents, such as epoxidation, substitution, etc.
4. The resulting intermediate is reacted with an appropriate amount of substrate to produce the final product.
Safety Information:
Safety information regarding (4R,12aS)-7-Methoxy-4-methyll-6, 8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxylic acid is currently limited, so it should be used with caution. Appropriate personal protective measures, such as wearing protective goggles, gloves and laboratory coats, are required for laboratory operations. In addition, proper handling and storage of all chemicals should be followed to ensure that they do not pose a hazard to humans or the environment. When using this compound, it is recommended to refer to the relevant literature and safety data forms for more detailed information on its safe use.
Last Update：2024-04-09 21:54:55
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