133775-25-4
(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
CAS: 133775-25-4
Molecular Formula: C12H13F2N3O2
133775-25-4 - Names and Identifiers
133775-25-4 - Physico-chemical Properties
| Molecular Formula | C12H13F2N3O2 |
| Molar Mass | 269.2473 |
| Storage Condition | -20℃ |
| Use | Uses (2R,3R)-2-(2, 4-difluorophenyl)-1-(1H-1,2, 4-triazol-1-yl) butane -2, 3-diol is a heterocyclic organic compound and can be used as a pharmaceutical intermediate. |
133775-25-4 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.714 ml | 18.57 ml | 37.141 ml |
| 5 mM | 0.743 ml | 3.714 ml | 7.428 ml |
| 10 mM | 0.371 ml | 1.857 ml | 3.714 ml |
| 5 mM | 0.074 ml | 0.371 ml | 0.743 ml |
Last Update：2024-01-02 23:10:35
133775-25-4 - Nature
| storage conditions | Inert atmosphere,2-8°C |
Last Update：2024-04-10 22:29:15
133775-25-4 - Introduction
(2R,3R)-2-(2, 4-difluorophenyl)-1-(1H-1,2, 4-triazol-1-yl) butane -2, 3-diol is an intermediate in the synthesis of efluconazole. Efluconazole (Efinaconaozle) is the first topical triazole antifungal drug. It was developed by DOW Pharmaceutical Company of Canada. It was approved by FDA on June 6, 2014. It is mainly used for the treatment of Trichophyton rubrum and Trichophyton plaster. The hand and foot moss (I. e. onychomycosis) caused by the fungus.
Last Update：2024-04-09 21:04:16
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