133922-58-4

133922-58-4 - Names and Identifiers

Name	ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE
Synonyms	ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE ethyl 3-amino-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate 1H-Pyrazole-4-carboxylic acid, 3-amino-5-(trifluoromethyl)-, ethyl ester
CAS	133922-58-4

133922-58-4 - Physico-chemical Properties

Molecular Formula	C7H8F3N3O2
Molar Mass	223.1525
Storage Condition	−20℃

133922-58-4 - Introduction

ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-is an organic compound with the chemical formula C8H8F3N3O2. Its main properties are as follows:

1. Appearance: colorless to light yellow liquid or crystal.
2. Solubility: Soluble in common organic solvents such as ethanol, dimethylformamide and dichloromethane.
3. relative density: about 1.45g/cm³.
4. Boiling point: about 260-261°C.

ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-has the following main uses:

1. Pesticide intermediates: It can be used as intermediates for the synthesis of some pesticides, such as pyrazolone pesticides.
2. Drug intermediates: It can be used to synthesize some drugs, such as antiepileptic drugs and antitumor drugs.
3. chemical reagents: it can be used in organic synthesis reactions, such as oxidation, reduction and coupling reactions.

The method for preparing ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-is generally the following steps:

1.2-trifluoromethyl -3,5-dinitropyridine and ethyl acetate react to generate 2-trifluoromethyl -3,5-dinitropyridine acetate.
2.2-Trifluoromethyl-3, 5-dinitropyridine acetate reacts with hydrated ammonia to generate ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-benzyl.

Last Update：2024-04-09 02:00:50