134002-25-8

134002-25-8 - Names and Identifiers

Name	3-(S)-(1-Carbamoyl-1,1-diphenylmethyl)pyrrolidine
Synonyms	3-(S)-(1-Carbamoyl-1 (3S)-diphenyl-3-Pyrrolidineacetamide 2,2-diphenyl-2-(pyrrolidin-3-yl)acetamide (S)-alpha,alphal-Diphenyl-3-pyrrolidineacetamide (S)-ALPHA,ALPHA-DIPHENYL-3-PYRROLLIDINEACETAMIDE 3-(S)-(1-CARBAMOYL-1,1-DIPHENYLMETHYL)PYRROLIDINE 3-(S)-(1-Carbamoyl-1,1-diphenylmethyl)pyrrolidine (S)-3-(1-Carbamoyl-1,1-diphenylmethyl)pyrrolidine (s),-L,L-dipenyl-3-pyrrolidine acetamide L-tartaric acid salt (S)-Alpha,Alphal-Diphenyl-3-Pyrrolidineacetamide-L-tartrate(Darifenacin)
CAS	134002-25-8
EINECS	1533716-785-6
InChI	InChI=1/C18H20N2O/c19-17(21)18(16-11-12-20-13-16,14-7-3-1-4-8-14)15-9-5-2-6-10-15/h1-10,16,20H,11-13H2,(H2,19,21)

134002-25-8 - Physico-chemical Properties

Molecular Formula	C18H20N2O
Molar Mass	280.36
Density	1.147±0.06 g/cm3(Predicted)
Melting Point	114-118 °C
Boling Point	488.5±45.0 °C(Predicted)
Flash Point	249.241°C
Vapor Presure	0mmHg at 25°C
pKa	15.70±0.50(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.596

134002-25-8 - Introduction

3-(S)-(1-carbamoyl-1, 1-diphenylmethyl)pyrrolidine, also known as 3-(S)-(1-aminomethyl-1,1-diphenylmethyl)pyrrolidine, is an organic compound. It has some of the following properties:

1. Appearance: 3-(S)-(1-carbamoyl-1, 1-diphenylmethyl) pyrrolidine is a colorless or pale yellow liquid.
2. melting point: its melting point range is wide, usually between 20-25 ℃.
3. Solubility: It is easy to dissolve in common organic solvents, such as methanol, ethanol, dimethylformamide, etc.

3-(S)-(1-carbamoyl-1, 1-diphenylmethyl) pyrrolidine has a wide range of applications in the pharmaceutical field, mainly as a catalyst and ligand in chiral synthesis. It can be used in the synthesis of chiral drugs, pharmaceutical intermediates and pesticides.

The method for preparing 3-(S)-(1-carbamoyl -1,1-diphenylmethyl) pyrrolidine is relatively complicated and is generally obtained by a multi-step reaction. Its preparation scheme needs to be combined with specific reaction system and reaction conditions, and the most common method is to catalyze asymmetric synthesis by chiral catalyst.

For safety information, 3-(S)-(1-carbamoyl-1, 1-diphenylmethyl) pyrrolidine chemicals need to be kept away from heat and sources of ignition. During use, care should be taken to prevent contact with skin and eyes and to avoid inhalation or swallowing. Wear suitable protective gloves and glasses and operate in a well-ventilated environment. In case of accidental contact, rinse immediately with plenty of water and seek medical assistance.

Last Update：2024-04-09 20:02:46