134168-97-1
3-Fluoro-5-bromoaniline
CAS: 134168-97-1
Molecular Formula: C6H5BrFN
134168-97-1 - Names and Identifiers
| Name | 3-Fluoro-5-bromoaniline |
| Synonyms | 3-Fluoro-5-bromoaniline 5-BroMo-3-fluoroaniline 3-BroMo-5-fluoro-phenylaMine Benzenamine, 3-bromo-5-fluoro- |
| CAS | 134168-97-1 |
134168-97-1 - Physico-chemical Properties
| Molecular Formula | C6H5BrFN |
| Molar Mass | 190.01 |
| Density | 1.694 |
| Boling Point | 246℃ |
| Flash Point | 102℃ |
| Appearance | Liquid |
| Color | Brown |
| pKa | 2.51±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
134168-97-1 - Risk and Safety
| UN IDs | UN2811 |
| Hazard Class | 6.1 |
134168-97-1 - Introduction
3-Bromo-5-fluoroaniline is an organic compound with the chemical formula C6H5BrFN. The following is a description of the properties, uses, preparation and safety information of 3-bromo-5-fluoroaniline:
Nature:
-Appearance: 3-Bromo-5-fluoroaniline is a colorless crystalline solid.
-Solubility: It has low solubility in water and can be dissolved in common organic solvents such as ethanol, methanol, and chloroform.
Use:
-3-Bromo-5-fluoroaniline is an organic synthesis intermediate that can be used to synthesize various organic compounds, such as drugs, pesticides and dyes.
-It can also be used as a catalyst or coordination ligand in chemical synthesis reactions.
Preparation Method:
-3-Bromo-5-fluoroaniline can be prepared in two common ways:
1. through the nucleophilic substitution reaction: the reaction of difluoroaniline with bromoethane to generate 3-bromo-5-fluoroaniline.
2. by ammonia polarization reaction: 3-bromo -5-fluoronitrobenzene and ammonia reaction, after reduction to generate 3-bromo -5-fluoroaniline.
Safety Information:
-3-Bromo-5-fluoroaniline has low toxicity, but it is still necessary to pay attention to safe operation, avoid inhalation, contact with skin and intake.
-Wear appropriate personal protective equipment such as lab gloves, goggles and lab coats during operation.
-Do not contact this compound with flammable substances, strong oxidants and strong acids to avoid unsafe chemical reactions.
-In the event of exposure to the compound, rinse the affected area immediately with plenty of water and seek medical attention for further treatment.
Nature:
-Appearance: 3-Bromo-5-fluoroaniline is a colorless crystalline solid.
-Solubility: It has low solubility in water and can be dissolved in common organic solvents such as ethanol, methanol, and chloroform.
Use:
-3-Bromo-5-fluoroaniline is an organic synthesis intermediate that can be used to synthesize various organic compounds, such as drugs, pesticides and dyes.
-It can also be used as a catalyst or coordination ligand in chemical synthesis reactions.
Preparation Method:
-3-Bromo-5-fluoroaniline can be prepared in two common ways:
1. through the nucleophilic substitution reaction: the reaction of difluoroaniline with bromoethane to generate 3-bromo-5-fluoroaniline.
2. by ammonia polarization reaction: 3-bromo -5-fluoronitrobenzene and ammonia reaction, after reduction to generate 3-bromo -5-fluoroaniline.
Safety Information:
-3-Bromo-5-fluoroaniline has low toxicity, but it is still necessary to pay attention to safe operation, avoid inhalation, contact with skin and intake.
-Wear appropriate personal protective equipment such as lab gloves, goggles and lab coats during operation.
-Do not contact this compound with flammable substances, strong oxidants and strong acids to avoid unsafe chemical reactions.
-In the event of exposure to the compound, rinse the affected area immediately with plenty of water and seek medical attention for further treatment.
Last Update：2024-04-09 02:00:42
