135330-08-4

Name	RP 54745
Synonyms	RP-54745 RP 54745 4-chloro-5-(1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)dithiol-3-one 3H-1,2-Dithiol-3-one, 4-chloro-5-(3,4-dihydro-1-methyl-2(1H)-isoquinolinyl)-
CAS	135330-08-4

Molecular Formula	C13H12ClNOS2
Molar Mass	297.82
Density	1.46±0.1 g/cm3(Predicted)
Boling Point	411.4±55.0 °C(Predicted)
pKa	-2.57±0.40(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
In vitro study	RP-54745 diminishes LPS-induced interleukin-1 (IL-1) production by murine peritoneal macrophages.
In vivo study	RP-54745 (5 mg/kg) is effective at moderating oral doses in different mouse models of induced arthritis and in the MRL/lpr mice, genetically predisposed to develop an autoimmune pathology including arthritic disorders. The clinical status of the MRL mice, and several of their disturbed biochemical and immunological parameters, improved after a 3-month treatment with RP-54745.

Last Update：2024-01-02 23:10:35

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Product Name: RP 54745 Visit Supplier Webpage Request for quotation
CAS: 135330-08-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

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135330-08-4

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