135582
2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindole-1,3-dione
CAS: 835616-60-9
Molecular Formula: C13H9FN2O4
135582 - Names and Identifiers
135582 - Physico-chemical Properties
| Molecular Formula | C13H9FN2O4 |
| Molar Mass | 276.22 |
| Density | 1.570±0.06 g/cm3(Predicted) |
| Melting Point | 254-256°C |
| Boling Point | 520.9±45.0 °C(Predicted) |
| Solubility | DMSO: 200 mg/mL |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 10.63±0.40(Predicted) |
| Storage Condition | 2-8°C |
135582 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.62 ml | 18.102 ml | 36.203 ml |
| 5 mM | 0.724 ml | 3.62 ml | 7.241 ml |
| 10 mM | 0.362 ml | 1.81 ml | 3.62 ml |
| 5 mM | 0.072 ml | 0.362 ml | 0.724 ml |
Last Update：2024-01-02 23:10:35
135582 - Reference Information
| Use | 2-(2, 6-dioxo-piperidin-3-yl) -4-fluoro-isoindole-1, 3-dione is an intermediate for the synthesis of N-[2-aminoethyl] pomalotamide TFA salt. N-[2-aminoethyl] pomilidamide TFA is a thalidomide derivative that is a potent inhibitor of TNF-α and is an anti-inflammatory and anti-neoplastic agent for the treatment of multiple myeloma. A ligand for the E3 ubiquitin ligase used in PROTAC technology. |
Last Update：2024-04-09 20:52:54
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