135634-18-3 - Names and Identifiers
Name | 2,4-Difluorophenyl-(4-piperidinyl)methanone oxime hydrochloride
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Synonyms | NH26248 138271-16-6 Paliperidone Impurity 30 (2, 4-dp)-piperidin-4-yl-methanone oximehcl (2,4-DIFLUOROPHENYL)(PIPERIDIN-4-YL)METHANONE OXIME HCL (2,4-Difluorophenyl)-4-piperidylMethanone OxiMe Hydrochloride 2,4-DIFLUOROPHENYL-(4-PIPERIDINYL)METHANONE OXIME HYDROCHLORIDE 2,4-Difluorophenyl-(4-piperidinyl)methanone oxime hydrochloride (2,4-Difluorophenyl)(piperidin-4-yl)methanone oxime hydrochloride (Z)-(2,4-Difluorophenyl)(piperidin-4-yl)methanone oxime hydrochloride (Z)-(2,4-Difluorophenyl)piperidin-4-ylmethanone oxime monohydrochloride (E)-1-(2,4-difluorophenyl)-N-hydroxy-1-piperidin-4-ylmethanimine hydrochloride
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CAS | 135634-18-3
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EINECS | 603-927-4 |
InChI | InChI=1/C12H14F2N2O.ClH/c13-9-1-2-10(11(14)7-9)12(16-17)8-3-5-15-6-4-8;/h1-2,7-8,15,17H,3-6H2;1H/b16-12+ |
135634-18-3 - Physico-chemical Properties
Molecular Formula | C12H15ClF2N2O
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Molar Mass | 276.71 |
Boling Point | 383.2°C at 760 mmHg |
Flash Point | 185.6°C |
Vapor Presure | 1.48E-06mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Almost white |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
135634-18-3 - Introduction
(2,4-Difluorophenyl)-(4-piperidinyl) methanone oxime hydrochloride, the chemical formula is C12H9F2N2O · HCl. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
(2,4-Difluorophenyl)-(4-piperidinyl) methanone oxime hydrochloride is a white crystalline powder with good solubility, soluble in polar solvents such as alcohol and DMF (dimethylformamide), slightly soluble in water. It is a weakly basic compound that can react with acids to form hydrochloride salts.
Use:
This compound is often used in some important reactions in organic synthesis, such as heterocyclization reactions and C- C bond formation reactions. It has important applications in drug synthesis and can be used to prepare a variety of biologically active compounds.
Preparation Method:
The preparation method of (2,4-difluorophenyl)-(4-piperidinyl) methanone oxime hydrochloride is as follows:
(2,4-Difluorophenyl)-(4-piperidinyl) methanone was first dissolved in hydrochloric acid, and then the reaction was stirred at room temperature to produce a white precipitate. The precipitate is washed, filtered and dried to give the pure product.
Safety Information:
This compound is a chemical and must be used under strictly controlled laboratory conditions. It may cause irritation and damage to the eyes, skin and respiratory tract, so it is necessary to wear appropriate protective equipment, such as laboratory gloves, safety glasses and protective masks. At the same time, avoid inhaling its dust or solution, and maintain good ventilation. If taken by mistake or inhaled by mistake, seek medical attention immediately.
Last Update:2024-04-09 21:11:58