1356582-71-2
Cbz-DL-Valinol
CAS: 1356582-71-2
Molecular Formula: C13H19NO3
1356582-71-2 - Names and Identifiers
| Name | Cbz-DL-Valinol |
| Synonyms | Cbz-DL-Valinol benzyl (1-hydroxy-3-methylbutan-2-yl)carbamate |
| CAS | 1356582-71-2 |
1356582-71-2 - Physico-chemical Properties
| Molecular Formula | C13H19NO3 |
| Molar Mass | 237.29 |
1356582-71-2 - Introduction
Cbz-DL-valinol is an organic compound whose chemical name is N-benzylaminoacetate-L-valinol. It has a white to light yellow crystalline solid, soluble in some organic solvents such as methanol and ethanol, and insoluble in water.
Cbz-DL-valinol is commonly used as a chiral intermediate, mainly used in the synthesis of drugs and pesticides. The valinol moiety is a chiral alcohol, and the stereochemical configuration of the synthetic target compound can be adjusted by changing the chiral reactants in the synthesis.
A common method for preparing Cbz-DL-valinol is by reacting DL-valinol with N-benzyl dimethylaminoacetate to form N-benzyl-valinol ester, followed by hydrochloric acid treatment and deprotection reaction to obtain the target product Cbz-DL-valinol.
Regarding safety information, Cbz-DL-Valinol is a chemical and requires attention to safe operation. It may be irritating to the skin, eyes and respiratory tract, so wear protective equipment to avoid inhalation and contact with skin. If contact or inhalation occurs, rinse immediately with water and seek medical help. During storage and handling, avoid contact with oxidants, acids and alkalis to prevent dangerous reactions.
Please note that the information provided here is only a brief introduction. Specific properties, uses, methods and safety information need to be determined according to specific experimental conditions and material safety data sheets. When working with chemicals, always follow proper procedures and safety guidelines.
Cbz-DL-valinol is commonly used as a chiral intermediate, mainly used in the synthesis of drugs and pesticides. The valinol moiety is a chiral alcohol, and the stereochemical configuration of the synthetic target compound can be adjusted by changing the chiral reactants in the synthesis.
A common method for preparing Cbz-DL-valinol is by reacting DL-valinol with N-benzyl dimethylaminoacetate to form N-benzyl-valinol ester, followed by hydrochloric acid treatment and deprotection reaction to obtain the target product Cbz-DL-valinol.
Regarding safety information, Cbz-DL-Valinol is a chemical and requires attention to safe operation. It may be irritating to the skin, eyes and respiratory tract, so wear protective equipment to avoid inhalation and contact with skin. If contact or inhalation occurs, rinse immediately with water and seek medical help. During storage and handling, avoid contact with oxidants, acids and alkalis to prevent dangerous reactions.
Please note that the information provided here is only a brief introduction. Specific properties, uses, methods and safety information need to be determined according to specific experimental conditions and material safety data sheets. When working with chemicals, always follow proper procedures and safety guidelines.
Last Update：2024-04-09 20:49:11
