1361237-41-3

1361237-41-3 - Names and Identifiers

Name	3-(Tetrahydrofurfuryloxypropyl)Heptamethyltrisiloxane
Synonyms	(TETRAHYDROFURFURYLOXYPROPYL)METHYLSILOXANE (TETRAHYDROFURFURYLOXYPROPYL)METHYLSILOXANE, 5cSt 3-(Tetrahydrofurfuryloxypropyl)Heptamethyltrisiloxane 3-(TETRAHYDROFURFURYLOXYPROPYL)HEPTAMETHYLTRISILOXANE 1,1,1,3,5,5,5-Heptamethyl-3-(3-((Tetrahydrofuran-2-Yl)Methoxy)Propyl)Trisiloxane Trisiloxane, 1,1,1,3,5,5,5-heptamethyl-3-[3-[(tetrahydro-2-furanyl)methoxy]propyl]-
CAS	1361237-41-3

1361237-41-3 - Physico-chemical Properties

Molecular Formula	C15H36O4Si3
Molar Mass	364.7
Boling Point	132-136°C / 2
Flash Point	>110°C (>230°F)
Specific Gravity	0.93
Sensitive	4: no reaction with water under neutral conditions
Refractive Index	1.426

1361237-41-3 - Reference Information

Application

3-(tetrahydrofuryloxypropyl) methyltrisiloxane is a tetrahydrofurfuryl alcohol compound, which can be used as an intermediate in pharmaceutical synthesis and An organic synthesis intermediate is mainly used in the laboratory research and development process and the chemical and pharmaceutical synthesis process.

Preparation

3-(tetrahydrofuryloxypropyl) methyltrisiloxane is prepared as follows: To a 1 liter 3-neck flask equipped with a magnetic stirrer, a tank thermometer, a dry ice condenser and a charging funnel Add 129.3g allypropoxymethyltetrahydrofuran. The flask was heated to 80°C, 8.1g of bis (trimethylsiloxy) methylsilane was added, and then 0.5g of Karstedt catalyst with a Pt concentration of 2% was added. Heat release was observed and additional 204.5g of bis (trimethylsiloxy) methylsilane was added while maintaining the temperature between 80 °-110°C. After the addition, 0.25g Karstedt catalyst was added, and the mixture was heated to 90°C and kept for 1 hour. The mixture was distilled through a short Vigreux column. 3-(tetrahydrofuryloxypropyl) methyltrisiloxane (GC purity 98.7%) was obtained, the yield was 84%, the boiling point was 132-6 ℃/2mm, and the density was 0.9250 at 25 ℃.

Last Update：2024-04-10 22:29:15