136547-16-5

136547-16-5 - Names and Identifiers

Name	Pyrimidine, 4-(trifluoromethyl)- (9CI)
Synonyms	4-Trifluoromethylpyrimidine 4-(Trifluoromethyl)Pyrimidine Pyrimidine, 4-(trifluoromethyl)- Pyrimidine, 4-(trifluoromethyl)- (9CI)
CAS	136547-16-5
InChI	InChI=1/C5H3F3N2/c6-5(7,8)4-1-2-9-3-10-4/h1-3H

136547-16-5 - Physico-chemical Properties

Molecular Formula	C5H3F3N2
Molar Mass	148.09
Density	1.353g/cm³
Boling Point	137.9°C at 760 mmHg
Flash Point	37.2°C
Vapor Presure	8.58mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.415

136547-16-5 - Introduction

4-Trifluoromethylpyrimidine is an organic compound, also known as TFT or F4MP. The following is a description of its nature, use, formulation and safety information:

Nature:
- 4-trifluoromethylpyrimidine is a colorless crystal, the common physical form is powder.
-It is stable at room temperature and has high thermal stability.
-its chemical nature is more inert, not easy to react with other compounds.

Use:
- 4-trifluoromethylpyrimidine is widely used in the field of medicine, as an active ingredient for the synthesis of antiviral, anticancer and antibacterial drugs.
-It is also used as a synthetic intermediate for optical materials, catalysts and polymer materials.

Preparation Method:
The preparation of-4-trifluoromethylpyrimidine is usually carried out in two steps.
1. First, trifluoroethanone and isocyanate are reacted under basic conditions to obtain N-trifluoroacetylpurine.
2. On the basis of the first step, iodic acid is used to react with sodium sulfite, and a solvent is added to obtain 4-trifluoromethylpyrimidine.

Safety Information:
- 4-trifluoromethylpyrimidine is an organic compound, which has certain potential harm to human body.
-Wear appropriate personal protective equipment such as glasses, gloves and protective clothing during handling and operation.
-In case of skin contact or inhalation, rinse immediately with plenty of water and seek medical help.
-Keep away from sources of heat and ignition during storage and handling.

Last Update：2024-04-09 21:01:54