136735-95-0

136735-95-0 - Names and Identifiers

Name	(+)-1,2-Bis((2S,5S)-2,5-dimethylphospholano)benzene
Synonyms	(S,S)-ME-DUPHOS (S,S)-METHYL-DUPHOS (+)-1,2-BIS[(2S,5S)-2,5-DIMETHYLPHOSPHOLANO]BENZENE (+)-1,2-Bis((2S,5S)-2,5-dimethylphospholano)benzene (+)-1,2-Bis[(2S,5S)-2,5-diMethylphospholano]benzene kanata purity (+)-1,2-Bis((2S,5S)-2,5-diMethylphospholano)benzene (S,S)-Me-DUPHOS (2S,2'S,5S,5'S)-2,2',5,5'-TETRAMETHYL-1,1'-(O-PHENYLENE)DIPHOSPHOLANE (2S,2'S,5S,5'S)-2,2',5,5'-TETRAMETHYL-1,1'-(1,2-PHENYLENE)DIPHOSPHOLANE
CAS	136735-95-0

136735-95-0 - Physico-chemical Properties

Molecular Formula	C18H28P2
Molar Mass	306.36
Melting Point	67-76°C
Boling Point	415.0±15.0 °C(Predicted)
Specific Rotation(α)	D25 +476± 5° (c = 1 in hexane)
Water Solubility	Insoluble in water.
Appearance	crystal
Color	white
BRN	4810602
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Air Sensitive

136735-95-0 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
FLUKA BRAND F CODES	1-10

136735-95-0 - Introduction

()-1,2-Bis((2S,5S)-2,5-dimethylphospholano)benzene is an organic compound with the chemical formula C16H22P2.

Nature:
( )-1,2-Bis((2S,5S)-2,5-dimethylphospholano)benzene is a colorless liquid with low volatility. It can be dissolved in many organic solvents, such as ethanol, ether and dimethylformamide. The compound has a melting point of -30°C and a boiling point of 140-150°C.

Use:
( )-1,2-Bis((2S,5S)-2,5-dimethylphospholano)benzene is a chiral ligand with a wide range of applications in organic synthesis. It can be used as a ligand for catalysts and participate in asymmetric catalytic reactions, such as asymmetric hydrogenation and asymmetric nucleophilic substitution reactions. In addition, it can also be used as a ligand in metal organic chemistry and organic synthesis reactions.

Preparation Method:
( )-1,2-Bis((2S,5S)-2,5-dimethylphospholano)benzene can be prepared by multiple steps of synthesis. A common method is to react acetophenone with phosphorus aluminum chloride to obtain the corresponding aryl phosphorus compound, and then obtain the target product through reduction reaction and separation and purification.

Safety Information:
( )-1,2-Bis((2S,5S)-2,5-dimethylphospholano)benzene is relatively safe under normal conditions of use. However, since it is an organic compound, necessary safety measures should be taken when handling it, such as wearing protective glasses and gloves, and ensuring that it is operated under well-ventilated conditions. In addition, contact with oxidizing agents and strong acids should be avoided to avoid dangerous reactions. If the substance is ingested or inhaled, seek medical attention immediately.

Last Update：2024-04-10 22:29:15