137419-24-0
tert-butyl 1'H-spiro[indene-1,4'-piperidine]-1'-carboxylate
CAS: 137419-24-0
Molecular Formula: C18H23NO2
137419-24-0 - Names and Identifiers
| Name | tert-butyl 1'H-spiro[indene-1,4'-piperidine]-1'-carboxylate |
| Synonyms | LogP CHEMBRDG-BB 4011973 1'-BOC-SPIRO(INDENE-1,4'-PIPERIDINE) ethyl spiro[indene-1,4'-piperidine] -3-carboxylate tert-butyl spiro[indene-1,4'-piperidine]-1'-carboxylate tert-Butyl-1'H-spiro[inden-1,4'-piperidin]-1'-carboxylat tert-Butyl spiro[1H-indene-1,4'-piperidine]-1'-carboxylate tert-butyl 1'H-spiro[indene-1,4'-piperidine]-1'-carboxylate TERT-BUTYL 1'H-SPIRO[INDENE-1,4'-PIPERIDINE]-1'-CARBOXYLATE Spiro[1H-indene-1,4'-piperidine]-1'-carboxylic acid 1,1-diMethyl ethyl ester |
| CAS | 137419-24-0 |
| InChI | InChI=1/C18H23NO2/c1-17(2,3)21-16(20)19-12-10-18(11-13-19)9-8-14-6-4-5-7-15(14)18/h4-9H,10-13H2,1-3H3 |
137419-24-0 - Physico-chemical Properties
| Molecular Formula | C18H23NO2 |
| Molar Mass | 285.38 |
| Density | 1.13±0.1 g/cm3(Predicted) |
| Boling Point | 406.2±45.0 °C(Predicted) |
| Flash Point | 199.5°C |
| Vapor Presure | 8.28E-07mmHg at 25°C |
| pKa | -0.79±0.20(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.578 |
137419-24-0 - Introduction
tert-butyl lH-spiro [indene-l, 4-piperidine]-l-carboxylate is an organic compound whose chemical formula is C14H17NO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
tert-butyl lH-spiro [indene-l, 4-piperidine]-l-carboxylate is a solid material having a white to pale yellow crystalline form. It has low solubility and is almost insoluble in water, but can be dissolved in many organic solvents. Its melting point is in the range of 80-82°C.
Use:
tert-butyl 1H-spiro [indene-1,4-piperidine]-1-carboxylate is mainly used in the field of organic synthesis. It is often used as an intermediate in the preparation of other organic compounds. It also has potential applications in the field of medicine, for example as a lead compound for antiepileptic and sedative drugs.
Preparation Method:
tert-butyl 1H-spiro [indene-1,4-piperidine]-1-carboxylate can be prepared by esterification of 1,4-dihydroxy-8-piperidinecarboxylic acid and tert-butanol. The reaction is generally carried out under an inert atmosphere and requires the use of an acid catalyst to facilitate the reaction.
Safety Information:
Safety information for tert-butyl 1H-spiro [indene-1,4-piperidine]-1-carboxylate does not provide quantitative data and therefore the specific risk is unknown. Appropriate personal protective measures, such as wearing protective gloves and safety glasses, should be taken as part of routine laboratory operations. Any operation should be carried out under well-ventilated conditions to avoid inhalation of harmful gases or vapours. When using this compound, follow the relevant safety guidelines and regulations.
Nature:
tert-butyl lH-spiro [indene-l, 4-piperidine]-l-carboxylate is a solid material having a white to pale yellow crystalline form. It has low solubility and is almost insoluble in water, but can be dissolved in many organic solvents. Its melting point is in the range of 80-82°C.
Use:
tert-butyl 1H-spiro [indene-1,4-piperidine]-1-carboxylate is mainly used in the field of organic synthesis. It is often used as an intermediate in the preparation of other organic compounds. It also has potential applications in the field of medicine, for example as a lead compound for antiepileptic and sedative drugs.
Preparation Method:
tert-butyl 1H-spiro [indene-1,4-piperidine]-1-carboxylate can be prepared by esterification of 1,4-dihydroxy-8-piperidinecarboxylic acid and tert-butanol. The reaction is generally carried out under an inert atmosphere and requires the use of an acid catalyst to facilitate the reaction.
Safety Information:
Safety information for tert-butyl 1H-spiro [indene-1,4-piperidine]-1-carboxylate does not provide quantitative data and therefore the specific risk is unknown. Appropriate personal protective measures, such as wearing protective gloves and safety glasses, should be taken as part of routine laboratory operations. Any operation should be carried out under well-ventilated conditions to avoid inhalation of harmful gases or vapours. When using this compound, follow the relevant safety guidelines and regulations.
Last Update：2024-04-09 20:49:11
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CAS: 137419-24-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 137419-24-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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