1380202-32-3 - Names and Identifiers
1380202-32-3 - Physico-chemical Properties
| Molecular Formula | C8H7F3O
|
| Molar Mass | 176.1357896 |
1380202-32-3 - Introduction
2,2-difluoro-2-(2-FLUOROPHENYL)ETHANOL is an organic compound with the chemical formula C8H7F3O. It has the appearance of a colorless liquid with a special pungent odor. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Physical Properties: 2,2-difluoro-2-(2-FLUOROPHENYL)ETHANOL is soluble in organic solvents such as alcohols, ethers and aromatic hydrocarbons; Hardly soluble in water.
-Chemical properties: It is a compound that forms hydrogen bonds in the molecule, which can be easily oxidized and reduced.
Use:
2,2-difluoro-2-(2-FLUOROPHENYL)ETHANOL has many applications in chemistry:
-As an important intermediate in synthesis, used in the synthesis of other organic compounds.
-Used in medicinal chemistry research, as a raw material for drug synthesis.
-In some specific chemical reactions, as a catalyst or solvent.
Method:
The preparation of 2,2-difluoro-2-(2-FLUOROPHENYL)ETHANOL is usually carried out through the following reaction path:
-First, 2,2-difluoro-1-chloroethane reacts with 2-fluorophenylboronic acid to obtain 2,2-difluoro-1-phenylethylene.
-Then, 2,2-difluoro-1-phenylethylene is reacted with sodium hydroxide in a mixed solvent of water and dichloromethane to obtain 2,2-difluoro-2-(2-FLUOROPHENYL)ETHANOL.
Safety Information:
For the safety of 2,2-difluoro-2-(2-FLUOROPHENYL)ETHANOL, the following points should be observed:
-The compound has a pungent odor, and care should be taken to avoid inhalation and contact with skin and eyes during use.
-Good ventilation measures should be taken during operation to avoid inhalation of its vapor.
-Personal protective equipment such as protective gloves, glasses and protective clothing are recommended.
-If you accidentally come into contact with this compound, immediately flush the affected area with plenty of water and seek medical attention.
-Waste should be disposed of in accordance with local environmental regulations.
Last Update：2024-04-09 21:01:54