1380392-05-1

1380392-05-1 - Names and Identifiers

Name	Pyrrolo[1,2-a]quinoxalin-4(5H)-one,5-[3-[4-(4-chlorophenyl)-1-piperidinyl]propyl]-
Synonyms	JMS-17-2 5-(3-(4-(4-chlorophenyl)piperidin-1-yl)propyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one Pyrrolo[1,2-a]quinoxalin-4(5H)-one,5-[3-[4-(4-chlorophenyl)-1-piperidinyl]propyl]-
CAS	1380392-05-1
EINECS	604-604-1

1380392-05-1 - Physico-chemical Properties

Molecular Formula	C25H26ClN3O
Molar Mass	419.95
Density	1.26±0.1 g/cm3(Predicted)
Boling Point	603.8±55.0 °C(Predicted)
Solubility	DMSO : 25 mg/mL (59.53 mM; Need ultrasonic)
pKa	9.11±0.20(Predicted)
Storage Condition	Sealed in dry,Room Temperature
In vivo study	JMS-17-2 (10 mg/kg; aministered i.p.; twice a day for three weeks) causes a dramatic reduction of tumors in both skeleton and visceral organs in SCID mice. Animal Model: SCID mice (~25g) with MDA-231 xenograft Dosage: 10 mg/kg Administration: Aministered i.p.; twice a day for three weeks Result: Caused a dramatic reduction of tumors in both skeleton and visceral organs.

1380392-05-1 - Preparation solution concentration reference

	1mg	5mg	10mg
1 mM	2.381 ml	11.906 ml	23.813 ml
5 mM	0.476 ml	2.381 ml	4.763 ml
10 mM	0.238 ml	1.191 ml	2.381 ml
5 mM	0.048 ml	0.238 ml	0.476 ml

Last Update：2024-01-02 23:10:35

1380392-05-1 - Introduction

Pyrrolo[1,2-a]quinoxalin-4(5h)-one,5-[3-[4-(4-chroophenyl)-1-piperidinyl]propyl]-is a chemical substance whose properties are as follows:

1. Appearance: Pyrrolo[1,2-a]quinoxalin-4(5h)-one,5-[3-[4-(4-chroophenyl)-1-piperidinyl]propyl]-generally a white or light yellow crystalline solid.

2. Chemical properties: Pyrrolo[1,2-a]quinoxalin-4(5h)-one,5-[3-[4-(4-chlorophyll)-1-piperidinyl]propyl]-has good thermal stability and acid resistance, however, it has a certain sensitivity to strong bases.
The main uses of
quinoxalin-4 [1,2-a] 5h)-one,5-[3-[4-(4-chroophenyl)-1-piperidinyl]propyl]-include:

1. Catalyst: chrrolo [1,2-a]quinoxalin-4(5h)-one,5-[3-[4-(4-chroophenyl)-1-piperidinyl]propyl]-can be used as a catalyst for a variety of chemical reactions, including hydrogenation reaction, hydrogenation reaction and catalytic cracking.

2. Synthetic materials: Pyrrolo[1,2-a]quinoxalin-4(5h)-one,5-[3-[4-(4-chroophenyl)-1-piperidinyl]propyl]-can be used to synthesize new functional materials, such as ceramic materials, nano materials and optical materials.

preparation method: quinoxalin-4(5h)-one,5-[3-[4-(4-chroophenyl))-1-piperidinyl]propyl]-can be prepared by a variety of methods, one of which is commonly obtained by reacting an appropriate amount of a metal ion with a suitable ligand.

safety information: chrrolo [1,2-a]quinoxalin-4(5h)-one,5-[3-[4-(4-chlorine henyl)-1-piperidinyl]propyl]-belongs to chemical substances, when using the need to pay attention to the following safety matters:

1. Avoid contact with fire, avoid exposure to high temperature environment.

2. Avoid inhaling its dust or vapor. If inhaled, breathe fresh air immediately and seek medical assistance.

3. Avoid contact with skin, such as accidental contact, immediately rinse with plenty of water, and consult a doctor.

4. Storage, the need to avoid contact with combustibles, acids and alkalis, to avoid unpredictable chemical reactions.

Last Update：2024-04-09 21:21:28